Oluwatosin ⚕️

Welcome to the month of April… the only ‘pril’ that isn’t an ACE inhibitor.

🫀Heart failure in 2026: we are no longer treating symptoms. We are redesigning the disease. The latest evidence update reminds us of something profound: Heart failure is no longer a single entity. It is a spectrum, and now, finally, we are treating it as one. Several paradigm shifts stand out. 1. SGLT2 inhibitors are no longer “add-on” therapy. They are foundational across the entire EF spectrum. From HFrEF to HFpEF, the data are now consistent. Not just symptom improvement, but hard outcomes. This may be the most important unifying therapy in modern HF. 2. HFpEF is no longer a therapeutic desert. For the first time, we have real disease-modifying options: Finerenone → outcome reduction across EF ranges GLP-1 / dual incretin therapies → targeting the obesity phenotype Structural and metabolic mechanisms are finally being addressed We are moving from “HFpEF frustration” → HFpEF phenotyping. 3. Acute heart failure is no longer about stabilization. It is about early transformation. The new paradigm: Start GDMT in-hospital Optimize rapidly Treat beyond congestion Decongestion is still important, but it is no longer the goal. Disease modification starts on day 1. 4. Decongestion is becoming precision medicine Urine sodium-guided therapy Early escalation of loop diuretics Sequential nephron blockade Not just “give furosemide”, but measure, adjust, and target response. 5. Devices are no longer rescue therapy, they are integrated care TEER expanding from mitral → tricuspid Pulmonary artery pressure monitoring reducing hospitalizations Remote hemodynamics shaping outpatient management The boundary between ICU, ward, and home is dissolving. 6. The biggest problem is no longer evidence. It is implementation. We already have: Quadruple therapy Proven outcome benefits Yet many patients never reach target doses. The gap is no longer science. It is execution. 🤓Final message Heart failure care has entered a new era: Mechanism-based therapy Early aggressive optimization Phenotype-driven treatment And perhaps most importantly: We are no longer chasing symptoms. We are altering the trajectory of the disease. 📃Reference Liori S, et al. Heart failure evidence update 2026. Heart Failure Reviews. 2026. doi.org/10.1007/s10741…

@Ferelabi5 Congratulations Egbon ❤️

Grateful to God 👊

@thowluwh @Nigerian_Doctor Congratulations, Chief!

Mccqe 1 ✅

The best time to meet the Love of your life is in medical school. The second best time is housemanship, if God pity you, NYSC After that, you fit pick beans tire

Never been this cooked for an exam all my life. Pharmacology, o tun gbe mi de be 😩

Clonidine

@Davzoid_ Antimicrobials

@boyedeMD How far? Where this one dey?

Imipenem has a toxic metabolite. Cilastatin inhibits dehydropeptidase I; the enzyme that converts imipenem to its toxic metabolite.

Drug of choice for invasive candidiasis? A) Fluconazole B) Amphotericin B C) Nystatin D) Clotrimazole

Drug of choice for myasthenic crisis? A. Pyridostigmine B. IVIG / Plasmapheresis C. Corticosteroids only D. Methotrexate

Which drug is the first-line treatment for chronic stable angina?

Drug of choice for NSAID-induced gastric ulcer? A) PPI (Omeprazole) B) H2 blocker (Ranitidine) C) Antacid D) Metoclopramide

The most specific antibody for RA is? A. ANA B. Anti-CCP C. Anti-Smith D. Anti-centromere

What is the primary use of pilocarpine? A) Glaucoma B) Hypertension C) Asthma D) Diabetes

A 55-year-old diabetic patient with proteinuria has BP 160/95 mmHg. Which is the drug of choice? A) Amlodipine B) Hydrochlorothiazide C) Enalapril D) Propranolol

A patient on amlodipine develops ankle swelling. This occurs due to: A) Sodium retention B) Increased capillary hydrostatic pressure C) Reduced cardiac output D) Lymphatic obstruction

In the treatment of tuberculosis, which drug is most commonly associated with optic neuritis❓ A. Isoniazid B. Rifampicin C. Pyrazinamide D. Ethambutol

@OgagunQ Cold shivers 🥶😭 Come April, it’s our turn 😭

Pharmacology final exam - invigilator dropped 16 booklets for my guy in the first row. Man wanted to start distributing. Lecturer was like "Hey bro, they are all for you". 15 minutes into the exam he asked for a chilled coke and the supervisor bought it for him with his money 😂

@Barakahh_b @omo_Akinbile Or the SR is preparing for primaries

Plot twist: You have a strict SR You'd go through everything you can imagine aside being released to go have a free day😂