Sharmistha Sinha

We report self-assembled bacterial shell proteins that act as stable biological semiconductors, generating strong photocurrents without external bias pubs.rsc.org/en/content/art… #ChemicalScience #Bioelectronics #ProteinEngineering @Silkybedi2 @smrose_24 @INSTMohali

INST Mohali Hiring PhD students (inst.ac.in/careers). Open positions at the Sinhalab. Do write to us (sinhas@inst.ac.in) if you are "Dreamers who pipette with a purpose"! @INSTMohali

This work brings us closer to biosensing tools for neurodegenerative diseases. Grateful to my team and Dr. Deepak Sharma's lab for a fantastic collaboration! Read the paper: pubs.rsc.org/en/Content/Art… @sinhalabinst @INSTMohali

Our findings: These nanoclusters show distinct signals based on the type of α-synuclein aggregate they encounter—enabling label-free detection and discrimination.

Excited to share our latest work from the Sinha Lab @ INST Mohali, together with Dr. Deepak Sharma @ IMTECH Chandigarh, just published in Nanoscale! We developed charge-sensitive gold nanoclusters to distinguish α-Syn aggregates, a key step toward early Parkinson’s detection.

Join the Sinha Lab at INST Mohali 🧬 Research on biomolecular self-assembly, synthetic biology, and disease mechanisms. 📩 Apply: sinhas[at]inst[dot]ac[dot]in 🔗 More info: inst.ac.in/scientist/24-s…; inst.ac.in/careers #PhDPosition #SyntheticBiology #Biophysics

Silky just defended her thesis today! From BMC proteins to bioelectronics wizardry, she's been assembling more than just molecules. Go Dr. Silky! Dr Asifkhan Shanavas and Dr. Surajit Karmakar along with Dr. Kausik Chakraborty (IGIB) served the committee @Silkybedi2 @INSTMohali

Our lab at @INSTMohali will be hiring a Ph.D. student in the upcoming August session. If you are interested in working with us, consider applying for the same. If you would like to know more about our research, please check out our personal group website. amitmondal23.wixsite.com/my-site

INST Mohali celebrated its Foundation day on 25th March 2025. Professor Laxmidhar Behera, Director, IIT Mandi, delivered a Foundation Day lecture on the topic “History of AI and Some Selected Applications”. The winners of the Sport Day-2025 meet have also been felicitated.

🔬 Love molecular self-assembly? 🧩 Sinha Lab @ INST Mohali is decoding bacterial microcompartments for synthetic biology & disease research! Got a CSIR/UGC-JRF? Join us! ✉️ sinhas[at]inst.ac.in More: inst.ac.in/scientist/24-s… #PhD #Biophysics #Nanoscience

Breaking up translation condensates in cancer: nature.com/articles/s4155…

Latest lab review- The Gut microbiota-Immune-Brain axis: Therapeutic Implications. Just out in @CellRepMed Well done @kjdoriordan @gerrymoloney @LilyKeane & @UCCpsychiatry cell.com/cell-reports-m…

A globular protein exhibits rare phase behavior and forms chemically regulated orthogonal condensates in cells: nature.com/articles/s4146…

Genes That Stick Together, Work Together! A molecular life lesson: teamwork and proximity shape success! In nature, who you’re next to matters! Check our latest publication to learn more! doi.org/10.1016/j.bbag… @INSTMohali @Silkybedi2 @smrose_24

Aarcha presenting "Harnessing the Disorder" to design synthetic bioanoreactors at the Indian Biophysical Society Meeting 2025. #IBS2025 @INSTMohali @sinhalabinst

Bile acids stirring the pot in Parkinson’s? Lithocholic acid (LCA) speeds up α-synuclein clumping by 75%, while deoxycholic acid (DCA) takes a 30% nudge. Together, they’re not exactly brain-friendly! Check out our recent findings at doi.org/10.1021/acsche… @INSTMohali @IndiaDST