Cell Reports Medicine

The new issue is out! Cover: Li et al. shows unsafe drinking water is linked to multiple health risks globally. The cover image—an auction for "the last glass of pure water"—highlights urgent need for policy action to reduce water-related disease. Follow us on LinkedIn for more!

Online now: Psilocybin restores behavior and 5-HT2A signaling while reducing microglial density after chronic traumatic brain injury in rats dlvr.it/TT7kQt

Online now: Toward generalizable prediction of cancer signal using a cell-free DNA language model dlvr.it/TT7XmD

We're thrilled to announce the speaker lineup for @CellPressEvents @CPSOrganoidsNAMs27, including keynote speakers @DonIngber, @MummeryLab & Mark Skylar-Scott @StanfordDeptMed View the full lineup: hubs.li/Q04lQT4W0

Online now: Ion sequential therapy aligned with pathological changes enhances cardiac function after myocardial infarction dlvr.it/TT6pw3

Abstract submission for @CellPressEvents #CSCellDeath2026 closes tomorrow, June 19! Don’t miss this chance to present your research to an international audience and to apply for trainee scholarship and family support awards.   Submit here: hubs.li/Q04lQRzt0

Online now: Patient-derived organoids predict personalized drug response and reveal alternative therapeutic options in glioblastoma dlvr.it/TT5slJ

Online now: HIV tri-specific killer engagers directly enhance NK cell function and safely expand NK cells in vivo dlvr.it/TT5H7v

Online now: STAT3 interference-driven nanomodulators reverse lipid metabolism-associated chemoresistance and potentiate metalloimmunotherapy in breast cancer dlvr.it/TT50Nc

Online now: Human primary antibody response to vaccination follows a partially sequential class-switching program with a checkpoint at IGHG2 dlvr.it/TT4JW1

Online now: Type I interferon signaling in hematopoietic cells impairs neutrophil antibacterial function in the middle ear during viral co-infection dlvr.it/TT42gc

Online now: Targeted extracellular vesicle-photoimmunotherapy remodels stromal-immune microenvironment to boost chemo-immunotherapy in preclinical models dlvr.it/TT3MkL

Online now: Salmonella vector creates de novo parvovirus that reduces solid tumors and forms antitumor immune memory dlvr.it/TT33S6

Online now: Metabolically engineered probiotic OMVs as nanovaccine mediating sequential immunomodulation for chronic bone infection immunotherapy dlvr.it/TT2Vb0

Online now: Emerging therapeutic strategies for mitochondrial DNA-related diseases dlvr.it/TT2Jvl

Online now: Comprehensive mapping of human CD4+ T cell epitopes for Nipah and measles as prototype Paramyxoviruses dlvr.it/TT1wMV

Online now: Patient-derived organoids from metastatic colorectal cancer mirror tumor heterogeneity and predict patient survival and drug sensitivity dlvr.it/TT1jv1

Online now: Druggable β-catenin palmitoyl-switch coordinates immune evasion via immunogenic ferroptosis resistance and PD-L1-mediated immunosuppression dlvr.it/TT0y2p

Online now: Intravenous human umbilical cord-derived mesenchymal stem cell transplantation for ischemic stroke (MERIT): A phase 1 trial dlvr.it/TSzy1b

Online now: Pro/synbiotics reduce systemic inflammation and improve gut health in Kenyan infants: An open label, randomized, 4-arm, phase II trial dlvr.it/TSzM55

Online now: Gut microbiome composition and functional potential associate with incident type 2 diabetes in 4,685 adults from a Swedish prospective cohort dlvr.it/TSz4Sn