Alphey Lab

Excited to see how UKRI is boosting Engineering Biology across the UK! 🚀 Check out the latest GSE blog post to see how UKRI is fueling innovation in the field. 👇 …mentscienceandengineering.blog.gov.uk/2025/06/30/cel…

🧬 Delighted to share our new review on synthetic HEG drives in Ae. aegypti. We examine challenges, propose the CHIROS framework to guide future dev, and discuss paths forward for this vector control strategy. @s_verkuijl @michell56085624 @AlpheyLab kwnsfk27.r.eu-west-1.awstrack.me/L0/https:%2F%2…

🚀 New paper out in @SciReports! We showed that not all RNA Pol III promoters are created equal—different promoters drive varying homing efficiencies in An. stephensi! 🧬✨ Congrats to the team! 👏 @AEstadea @michell56085624 @joshxdang @PhilipLeftwich nature.com/articles/s4159…

Had a fantastic time hosting @Jackson_Champer at our lab for a seminar on gene drive! 🎉🧬 Great discussions and loads of inspiration. Thanks for visiting us, and all the best with your future work! 🌟🦟✨ @michell56085624 @joshxdang

We engineered a CRISPR/Cas9 gene drive in Anopheles stephensi targeting the doublesex gene — aiming to disrupt malaria transmission at its source 🦟🧬 Promising inheritance, some fertility hurdles — but a big step forward! 📖 Read it here: parasitesandvectors.biomedcentral.com/articles/10.11…

🎄 As 2024 wraps up, we’re celebrating the progress we’ve made tackling real-world challenges through biology—together. 🚀 Huge thanks to our amazing team of scientists! 🌟 Merry Christmas & Happy New Year! 🎁🎉 Here’s to solving even bigger challenges in 2025! 💪

What is #genedrive and how could it help fight mosquito-borne diseases such as #malaria? Hear from experts from the @AlpheyLab @transm0 @imperialcollege and @TargetMalaria in this new @guardiannews piece penned by @taylor_rosie ➡️ theguardian.com/global-develop… @nikiwind @UofCalifornia

Interested in doing a PhD developing novel tools for the control of vector-borne diseases? Come join us @AlpheyLab @natalieprow13 @michell56085624 at @BiologyatYork. findaphd.com/phds/project/m…

Today is #WorldMosquitoDay. The mosquito is considered the deadliest animal in the world, acting as a powerful disease vector. Thank you to @genedrivenet for the opportunity to talk about my work and see the important work of other researchers. ➡️lnkd.in/e6HxPEeQ

“With #AedesAegypti 🦟becoming more resistant to insecticides, it is critical to develop new strategies to limit the spread of the diseases they transmit.” 🔬🧬 Hear more from Eunice Oluwatobiloba Adedeji @AlpheyLab @BiologyatYork. ➡️bit.ly/3WPM3XP #WorldMosquitoDay #EndDengue

Aedes🦟 are a major global health concern due to their role in spreading disease. This #WorldMosquitoDay, hear from researchers sharing facts about these 🦟, the diseases they carry & novel control tools🔬🧬 ➡️ bit.ly/3WPM3XP #EndDengue @PKU1898

On this #WorldMosquitoDay, we are facing the worst year on record for #dengue fever. @joshxdang @AlpheyLab @BiologyatYork shares his thoughts about this global health threat and tells us why new tools are needed to #EndDengue ➡️ genedrivenetwork.org/blog/dengue-ne…

If you ever run out of promoters to use for Anopheles stephensi transgenesis, try this out! 😀 Great work getting this out team. @ Joshua Southworth @michell56085624 @AEstadea @Mireia_Larrosa

The spread of Anopheles Stephensi🦟is threatening progress to #endmalaria in Africa. Last year, @Mireia_Larrosa, @AlpheyLab @UniOfYork presented her research on this vector @ASTMH. Learn more ➡️genedrivenetwork.org/blog/investiga…

ONLY 5 days left to apply!! There are 4 GenerationResearch Masters by research opportunties (2x @BiologyatYork and 2x @ChemistryatYork) Fully funded 1 year projects! Apply below or reach out if you have questions. generationresearch.ac.uk/phd-and-master…

A peek behind the scenes! The @AlpheyLab group is investigating using genetic methods to control mosquito-borne diseases

2 fully-funded 4 year #GenRes PhDs @BiologyatYork ! JUST 5 DAYS LEFT ! 1) biochemistry/plant science/biotechnology 2) infection/microbiome/bioinformatics generationresearch.ac.uk/phd-and-master… Looking for enthusiastic and motivated students, especially from underrepresented backgrounds

Alphey Lab alumni in GRC Genetic Biocontrol. 😀 Great to have a catch-up with everyone here. @PhilipLeftwich @ArthropodGen @matzenkj @XenWarPrin @s_verkuijl @joshxdang