Barmada Lab

Excited to share my thesis work! Using super-resolution microscopy and a new HaloTag-Nup107 mouse line, we find that 1) NPC biogenesis is upregulated during neuronal maturation and that 2) torsinA is essential for normal localization and assembly kinetics of neuronal NPCs. (1/N)

Excited to share that our latest preprint is out! Here we show that m6A modulates TDP43 RNA binding and that RNAs are hypermethylated in ALS. We also found if you knockdown an m6A reader, YTHDF2, you can mitigate disease related toxicity!

Excited to share that our latest preprint is out! Here we show that m6A modulates TDP43 RNA binding and that RNAs are hypermethylated in ALS. We also found if you knockdown an m6A reader, YTHDF2, you can mitigate disease related toxicity!