Lyssiotis Lab

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Lyssiotis Lab

Lyssiotis Lab

@LyssiotisLab

Cancer and Immune Metabolism Research Laboratory @UMRogelCancer, @UMPhysiology, @UMICHpancreas

University of Michigan Katılım Kasım 2015
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Lyssiotis Lab
Lyssiotis Lab@LyssiotisLab·
🔥Smoking hot new paper and tweetorial from @DJCalebC (collab with @ArulChinnaiyan)! 🔥 We are over the moon about this new work and its therapeutic implications for pancreatic cancer. Please have a read and share your thoughts/feedback! 🙏🏼
Caleb Cheng@DJCalebC

Beyond grateful to share that my main PhD thesis project, Targeting PIKfyve-driven lipid metabolism in pancreatic cancer (@LyssiotisLab @ArulChinnaiyan), has just been published in @Nature! @UMRogelCancer @UMICHpancreas @UMichMedSchool @UMichPath @UMichResearch @UMichCMB

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Dr. Catharine Young
Dr. Catharine Young@DrCatharineY·
As the world falls apart, so does the U.S. scientific system: >40% of NIH-funded scientists are canceling research >25% are laying off staff Two-thirds are telling students to leave academia The effects of this will be deep and felt for a very long time.
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Vishwa Deep Dixit
Vishwa Deep Dixit@VishwaDeepDixi1·
Caloric restriction in humans reveals immunometabolic regulators of health span | Science science.org/doi/10.1126/sc… Effects on thymus rejuvenation in humans (functional thymic vol and TRECs) were one of the unexpected finding from NIA funded CALERIE trial.
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Michigan Surgery
Michigan Surgery@UMichSurgery·
What comes next after a pancreatic cancer diagnosis? Surgical oncologist Evan Glazer, MD, PhD, offers guidance on where to seek treatment, what to expect from the process and more: michmed.org/dYZNx
Michigan Surgery tweet media
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Cell Metabolism
Cell Metabolism@Cell_Metabolism·
New! Online now: Cell Clustering Promotes a Metabolic Switch that Supports Metastatic Colonization dlvr.it/TRYmLH
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nature
nature@Nature·
Nature research paper: Catabolism of extracellular glutathione supplies cysteine to support tumours go.nature.com/4bBphKQ
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News from Science
News from Science@NewsfromScience·
Biomedical researchers breathed a collective sigh of relief after the White House loosened the purse strings that had hindered the U.S. National Institutes of Health from spending its 2026 budget on research grants. scim.ag/4uA29EX
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Max Kozlov
Max Kozlov@maxdkozlov·
We did not push any doomsday narrative; we reported the facts. The White House changed the rules for how agencies receive their appropriated budgets, limiting the NIH's access to its Congress-approved funds for 42 days and slowing down new awards. The data speaks for itself.
Max Kozlov tweet media
Jason Locasale@LocasaleLab

The “NIH is no longer functioning” narrative was always dramatically overstated. A delayed apportionment coming after a prolonged government shutdown was framed as institutional collapse rather than what it likely was: a lag in funding flow tied to broader delays in federal operations. That context was largely ignored. Instead, a handful of social influencers amplified by outlets like Science and Nature pushed a doomsday storyline that was far more dramatic than the underlying reality.

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Peggy Hsu MD PhD
Peggy Hsu MD PhD@PeggyPHsu·
Congrats to Varun, my technician (!), former @YatrikShahLab undergrad, soon-to-be MSTP student, for his first, first-authored publication examining the role of the labile iron pool in ferroptosis, now in press at JBC!!! sciencedirect.com/science/articl…
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山室 禎 (Yamamuro, Tadashi)
山室 禎 (Yamamuro, Tadashi)@TadashiYamamuro·
主著がCellに出ました！脂肪細胞ミトコンドリアがホスホエノールピルビン酸（PEP）の輸送を介して脂質新生を担うことを示しました。また、ミトコンドリアPEP輸送体としてSLC25A35を同定しました。梶村先生を初め、共著者の方々と、支えてくれた家族に深く感謝いたします。 cell.com/cell/abstract/…
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Developing Future Biologists
Developing Future Biologists@DFB_UM·
Are you still looking for a reason to donate to DFB tomorrow? We can name a few! ☺️ Please consider supporting DFB on Giving Blueday, either with a donation or just spreading the word on social media. Your voice makes a difference! Giving Blueday starts @ 12AM (EDT)! #goblue
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Max Kozlov
Max Kozlov@maxdkozlov·
The NIH is stepping back from 'top-down' science. Funding calls have plummeted by 90%, funneling billions into broad, 'investigator-initiated' ideas, rather than targeted, agency-driven ones. A massive shift for the American biomedical enterprise. nature.com/articles/d4158…
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Max Kozlov
Max Kozlov@maxdkozlov·
BREAKING: @rosadelauro announces at a House Oversight hearing with NIH director Jay Bhattacharya that OMB approved the agency's apportionment last night. That means the agency should* have access to its appropriated funds — 42 days after its spending bill passed.
Max Kozlov@maxdkozlov

Congress rejected massive cuts to US science budgets for 2026, but much of the money still isn’t flowing to researchers. The culprit? The White House Office of Management and Budget (OMB) is quietly slow-walking the release of funds. 🧵👇 For @Nature: nature.com/articles/d4158…

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Mark Histed
Mark Histed@HistedLab·
Writing out a conversation I’ve been having a lot at this conference: Things in US science are far, far worse than people know. Far worse than even other scientists know. 1/
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Zane Koch
Zane Koch@zanehkoch·
for a while i've had a slight fear that the bluetooth from my airpods could be frying my brain this weekend i pulled the raw data from a $30m government study of 1,679 mice blasted with cell phone radiation and reanalyzed it what i found was...not what I expected? 🧵
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Richard Possemato
Richard Possemato@RichPossemato·
Our model is that the function of exogenous cystine in cell culture media is principally to enable selenium import and selenoprotein function, particularly that of GPX4, and that this function can be substituted by beta-mercaptoethanol.
Richard Possemato tweet media
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Keşfet

@Cell_Metabolism @YatrikShahLab @uofcincy @SunLabUCin @rosadelauro @elonmusk @BarackObama @taylorswift13