Brönstrup Lab

🚀 Gemeinsamer Erfolg in der KI-Forschung! 🇩🇪🇫🇷 Ein deutsch-französisches Team, darunter DZIF-Wissenschaftler, erhält einen ERC Synergy Grant über 11 Mio. Euro. Ziel: Entwicklung eines KI-gestützten Ansatzes für die Suche nach neuen Antibiotika: dzif.de/de/erc-synergy… #ERCSyG

The HZI is looking for game changers in infection research and hiring Junior Research / Technology / Clinician-Scientist Group Leaders (with W1-professorship & tenure options). Join our program #HUMAN and study the complex interplay of humans & microbes! helmholtz-hzi.de/en/career/job-…

Our study on the last resort antibiotic colistin was just accepted by Angew Chem. (bit.ly/4dF8q9n). We reduce its renal cell toxicity by a two-component strategy and bioorthogonal chemistry. #chemicalbiology #antibiotics @helmholtz_hzi @_dzif @UniHannover

Volatile salinilactones, produced by the bacterium Salinispora, target disulfide-isomerases. See doi.org/10.1002/advs.2… in Advanced Science, by K. Jerye et al. of the @BronstrupLab. This is one of the first studies describing how bacterial volatiles act.

(2) Major topics (novel antiinfectives, computational methods, new concepts, two free-of-charge workshops) introduced by international speaker panel. @UniHannover #chemicalbiology #antibiotics #DrugDiscovery @helmholtz_hzi @_dzif @UniHannover @tuBraunschweig @EuroMedChem

Full program available, few days and <40 seats left for registration: 3rd Helmholtz Drug Discovery conference HDDC 2023 on May 15/16 in Braunschweig, Germany. helmholtz-hzi.de/de/hddc2023 (1)

@BronstrupLab correct link: pubs.rsc.org/en/content/art…

(2) @UniHannover #chemicalbiology #antibiotics #DrugDiscovery @helmholtz_hzi @_dzif @EuroMedChem

Our paper on siderophore conjugation with cleavable linkers to boost the potency of RNAP inhibitors has just appeared in Chemical Science (rsc.li/41WCR4Y). Thanks a lot to Carsten, Hazel, Anna et al. for the great work! (1)

(2) Major topics (novel antiinfectives, computational methods, new concepts, two free-of-charge workshops) introduced by international speaker panel. @UniHannover #chemicalbiology #antibiotics #DrugDiscovery @helmholtz_hzi @_dzif @UniHannover @tuBraunschweig @EuroMedChem

Abstract/talk submission closes this weekend: Please register for 3rdHelmholtz Drug Discovery conference HDDC 2023 on May 15/16 in Braunschweig, Germany. helmholtz-hzi.de/de/hddc2023 (1)

(2) Low registration fees. Please submit abstracts for short talks/posters. #chemicalbiology #antibiotics @helmholtz_hzi @_dzif @UniHannover

We announce the 3rd Helmholtz Drug Discovery conference HDDC 2023 on May 15/16 in Braunschweig, Germany. Major topics (novel antiinfectives, computational methods, novel concepts, success stories) introduced by international speaker panel. helmholtz-hzi.de/de/hddc2023

We are happy to enter the second round of the SPRIND challenge for novel antivirals. Thanks also to our partners, the Hilgenfeld lab, @biotechne and the Kikkert lab @LUMC_Leiden.

Optical modulation of antibiotic resistance by photoswitchable cystobactamids (M. Bronstrup et al.) @BronstrupLab onlinelibrary.wiley.com/doi/10.1002/ch…

@DirkTrauner Lieber Dirk, herzlichen Glückwunsch und alles Gute!

I am honored to announce that I will join the University of Pennsylvania this summer as a PIK Professor. penntoday.upenn.edu/news/dirk-trau…

@jcslab @Helmholtz_HZI Dear Jessica, thanks a lot for your lecture and the fruitful discussions with us!

Many thanks to @BronstrupLab for hosting me at @Helmholtz_HZI yesterday! So much fun giving my first in-person seminar in Germany and discussing diverse aspects of chemical bacteriology. Also a beautiful day to travel to Braunschweig!

@e_boros @Helmholtz_HZI @UniHannover Dear Eszter, thanks for the feedback!We also follow and like your work. Best regards, Mark

@BronstrupLab @Helmholtz_HZI @UniHannover Very cool! Going on our short list of papers for literature discussion at group meeting! 😀

Our joint paper with Doron Shabat on enzyme-activated, chemiluminescent siderophore-dioxetane probes for highly sensitive bacterial pathogen detection has been published in Angew Chem: bit.ly/376CUUu #chemicalbiology #antibiotics @helmholtz_hzi @_dzif @UniHannover