Fernando Gomez-Herreros Lab

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Fernando Gomez-Herreros Lab

Fernando Gomez-Herreros Lab

@FGH_Lab

DNA repair and Gene Expression in human disease. Andalusian research group. Find us at @IBiS_Sevilla

Seville, Spain Inscrit le Mayıs 2016
681 Abonnements647 Abonnés
Fernando Gomez-Herreros Lab retweeté
Diana Rubio
Diana Rubio@Diana_Rubio_·
Excited to see our research published!! 🎉 Amazing project in @FGH_Lab at @ibis_sevilla, @unisevilla "H263A and SCAN1/H493R mutant TDP1 block TOP1-induced double-strand break repair during gene transcription in quiescent cells and promote cell death" nature.com/articles/s4141…
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Fernando Gomez-Herreros Lab
Fernando Gomez-Herreros Lab@FGH_Lab·
These results support the potential role of TOP1-induced DSBs as a main contributor to certain hereditary neurological syndromes.
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Fernando Gomez-Herreros Lab
Fernando Gomez-Herreros Lab@FGH_Lab·
👉EWS::FLI1 modulates R-loop metabolism via DHX9, driving increased vulnerability to TOP1-targeting agents. 👉Targeting TOP1 in EWS cells destabilizes the genome and provokes strong replication stress and cell death in EwS cells and tumors
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Fernando Gomez-Herreros Lab retweeté
Joaquin Olmedo
Joaquin Olmedo@olmedo_pelayoJ·
Proud to announce that last Thursday I successfully defended my PhD thesis, “Understanding genome instability in Ewing sarcoma: from molecular mechanisms to novel therapeutic approaches”, at the @ibis_sevilla.
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Fernando Gomez-Herreros Lab retweeté
Hana Sedlackova
Hana Sedlackova@HanaSedlackova1·
📢 For all DNA fiber enthusiasts! 🟥🟩 We are thrilled to announce the release of our long-awaited AI-based workflow for the automated and quantitative analysis of DNA fibers. It's an exciting step forward—check it out on bioRxiv! lnkd.in/dQWUPtsP
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Fernando Gomez-Herreros Lab retweeté
RosadoLab
RosadoLab@RosadoLab·
Thrilled to share our latest work. Great collab with Costanzo, Masson, Freire and Reyes' labs. HMCES corrupts replication fork stability during base excision repair in homologous recombination–deficient cells | Science Advances science.org/doi/10.1126/sc…
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Fernando Gomez-Herreros Lab retweeté
Luis Lloredo Alix
Luis Lloredo Alix@llloredo·
Se ha filtrado el borrador de ley de universidades que está preparando la CAM. Si se aprueba, será la muerte de la universidad pública madrileña. Es escandaloso. No exagero. Se vienen tiempos oscuros como no espabilemos. Explico algunos puntos críticos. Va hilo. 👇
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Néstor García Rodríguez
Néstor García Rodríguez@NestorGarRod·
Happy to be awarded with a Consolidación investigadora grant to continue exploring ssDNA gap biology at @unisevilla and @cabimer. A postdoc position will be advertised soon. Stay tuned!
Agencia Estatal de Investigación@AgEInves

ℹ️ La @AgEInves publica la propuesta de resolución provisional de la convocatoria 2024 de ayudas para incentivar la consolidación investigadora. 🔗 aei.gob.es/sites/default/… 💰 41,9 M€ para consolidar la carrera de 221 investigadores/as en España.

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Fernando Gomez-Herreros Lab retweeté
Molecular Cell
Molecular Cell@MolecularCell·
Dynamic histone modification patterns coordinating DNA processes dlvr.it/THSzk5
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