Key Characteristics

23 posts

Key Characteristics

Key Characteristics

@KeyChars

Inscrit le Temmuz 2020
10 Abonnements40 Abonnés
Key Characteristics
Key Characteristics@KeyChars·
Excellent perspective in EHP: KCs "can be a springboard for the development of additional tools, technologies, protocols, and approaches for better exploring the hazard characteristics of agents that produce positive findings under specific sets of KCs." ehp.niehs.nih.gov/doi/10.1289/EH…
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Key Characteristics
Key Characteristics@KeyChars·
Thank you @EHPonline for the very nice Science Selection article featuring our recent paper with Cynthia Rider and colleagues on using the @KeyChars to assess chemical mixtures and cancer! @SRP_NIEHS
Environmental Health Perspectives@EHPonline

NEW SCIENCE SELECTION: A Framework for Cumulative Risk Assessment: Exploring the Carcinogenic Effects of Chemical Mixtures. Read the article ➡️ ow.ly/4O0t50GauLp @NIEHS @UCBerkeleySPH @busphEH @ucdavisCAES @EPAresearch @OEHHA

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Key Characteristics
Key Characteristics@KeyChars·
Read the insightful new perspective In @EHPonline from @IARCWHO scientists on how data from validated assays related to the key characteristics of carcinogens can be used to help prioritize and evaluate chemical risk factors in breast cancer. ehp.niehs.nih.gov/doi/10.1289/EH…
IARC@IARCWHO

New commentary from IARC Monographs highlights important gaps in evidence on causes of #BreastCancer & addresses how data from validated assays relevant to key characteristics of carcinogens @KeyChars can help prioritize chemicals for study & evaluation iarc.fr/news-events/ne…

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Key Characteristics
Key Characteristics@KeyChars·
Madia and colleagues at the European Commission's Joint Research Center utilized the key characteristics of carcinogens to integrate data across different systemic toxicity endpoints in their newly developed method for evaluating carcinogenicity hazard. link.springer.com/article/10.100…
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Key Characteristics
Key Characteristics@KeyChars·
A new paper details how the Key Characteristics (KCs) of carcinogens can strengthen hazard identification, lists assays and in vivo biomarkers that can be used to measure the KCs, and makes recommendations for future assay development cebp.aacrjournals.org/content/29/10/…
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Key Characteristics
Key Characteristics@KeyChars·
A working group led by Ivan Rusyn of Texas A&M have decided upon 12 KCs of hepatotoxicants.
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Key Characteristics
Key Characteristics@KeyChars·
Helen Guo, Stacy Ahn, and Luoping Zhang published a systematic review of chronic inflammation and immunosuppression (two characteristics of carcinogens) associated with benzene in humans oem.bmj.com/content/early/…
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Key Characteristics retweeté
UCB Superfund
UCB Superfund@ucbsrp·
In collaboration with scientists from OEHHA and IARC, our Research Translation Core has launched a website with resources for regulators and others interested in applying the key characteristics approach to hazard identification. @SRP_NIEHS @OEHHA @IARCWHO keycharacteristics.org
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Key Characteristics
Key Characteristics@KeyChars·
The working group to develop key characteristics of immunotoxicants will have its first meeting tomorrow morning.
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@NIEHS @UCB_EHS @EHPonline @OEHHA @IARCWHO @niehs @busphEH @ucdavisCAES