Mostoslavsky Lab

Really excited to share our new study, where we identified ZNF280A, a novel regulator of homologous recombination during DNA repair, linked to the human 22q11.2 distal deletion syndrome. A special shout out to @ThomasLClarke for leading the project! nature.com/articles/s4155…

@jdelriopantoja @HarvardGSAS @MGHCancerCenter Excellent article Jose!! proud to have you in my lab!!

Thanks @HarvardGSAS for featuring my story going beyond the dogmas of life. Cannot wait to formally share with the world all the cool science we’re doing at the @MostoslavskyLab @MGHCancerCenter. gsas.harvard.edu/news/beyond-do…

We’re happy to share our new study out today @NatureCellBio We show that a chromatin factor, ZNF280A, is required for DNA double strand break repair, linking its absence to clinical features in 22q11.2 distal deletion syndrome. @MostoslavskyLab nature.com/articles/s4155…

Excited to share our new work on how DNAJB1-PRKACA drives cancer cell growth in Fibrolamellar Carcinoma. @CD_AACR Thanks to all our collaborators and funding support. @FibroFoundation @AICF_nyc @DonaBertarelli @ForbeckForums @AlexLemonade

New Research: Subcellular one carbon metabolism in cancer, aging and epigenetics frontiersin.org/articles/10.33… #FrontiersIn #Epigenetics #Epigenomics

Really happy to share our new mini Review on One Carbon Metabolism and chromatin (fantastic job by @Tiz_bernasocchi. Out in @FrontGenetics frontiersin.org/journals/epige…

New in @sciencemagazine! Our study reveals how mutant IDH1 inhibition activates tumor immunity by inducing dsDNA sensing. Read more: science.org/doi/10.1126/sc… #CancerResearch #Cholangiocarcinoma #IDH1 1/n

Our lab does a little bit of everything centered around chromatin biology and metabolism. No previous research experience needed, but preferred!

This will be a full-time research technician position, roles will include assisting with basic science techniques, from standard molecular biology to advanced biochemistry, genetics, and in vivo work.

The Mostoslavsky Lab is looking for a highly motivated Research Technician interested in being part of our team for at least two years! Please share with your networks, and/or apply by sending an intro email with CV to: mostoslavskylab@gmail.com

@NCIYaminiDalal @NatureCellBio @NCIResearchCtr Ha ha! not sure I spoke about oncometabolites in the talk! :) We can chat about 2HG, probably the best oncometabolite example of how it affects chromatin by inhibiting all the a-KG dependent dyoxygenases.

Online now!! Really thrilled to share our latest work identifying a novel driver of metastasis, Gstt1, @NatureCellBio. A huge effort lead by Christina Ferrer and an incredible team of collaborators!! link.springer.com/article/10.103…

@NCIYaminiDalal @NatureCellBio @NCIResearchCtr @WeyemiLab It was a pleasure to see you all there!!

@NCIYaminiDalal @NatureCellBio @NCIResearchCtr Thanks Yamini!!!!

@JAguirreGhiso @NatureCellBio Ehhh! Thanks Julio!! so happy it is out! You heard it long ago!

@Lloyd_Bod @NatureCellBio Thanks Lloyd!!

@MostoslavskyLab @NatureCellBio Congrats Raul and team!🎊

@sciqst @NatureCellBio Thanks Raffaele!!!

Congratulations to the Mostoslavsky Lab team on this groundbreaking discovery! Identifying Gstt1 as a novel driver of metastasis could significantly advance our understanding and treatment of cancer. Tremendous work by Christina Ferrer and collaborators! For further questions or detailed biomedical reviews, check out sciqst.com, where AI can assist you with comprehensive insights. #Medicine #CancerResearch #Metastasis #OpenAI Sciqst powered by OpenAI.

@FrezzaLab @NatureCellBio Thanks Christian!!

@MostoslavskyLab @NatureCellBio great job all!

@FendtLab @NatureCellBio Thanks Sarah!!!

@BarakRotblat @NatureCellBio Thanks Barak!

@MostoslavskyLab @NatureCellBio Congrats!👏👏