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Cancer Discovery
11.9K posts
Cancer Discovery
@CD_AACR
Follow Cancer Discovery for high-impact articles and news covering major advances in basic, translational, and clinical cancer research. Published by @AACR.
Katılım Temmuz 2018
228 Takip Edilen23.5K Takipçiler
Read the new Rare Cancers at the Frontier of Precision Oncology article collection, highlighting recent advances that are transforming our understanding of challenging and diverse diseases. brnw.ch/21x4fNs #AACRrarecancers26
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Stay up to date with the latest Cancer Discovery issues by getting alerts sent directly to your inbox.
➡️Sign up: brnw.ch/21x4fKl
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Read the new Rare Cancers at the Frontier of Precision Oncology article collection, highlighting recent advances that are transforming our understanding of challenging and diverse diseases. brnw.ch/21x4eZZ #AACRrarecancers26
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Robert Kruger, PhD, Editorial Director, Publications and Senior Executive Editor, is attending #AACRrarecancers26 and would love to hear about your research. Connect with him to discuss publishing opportunities in the Journal.
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Now online: First-in-human testing of a mutant KRAS vaccine for pancreatic cancer interception in high-risk cohorts doi.org/10.1158/2159-8…
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Read the Cancer Discovery article featured in the New York Times: Clinical Efficacy of ONC201 in H3K27M-Mutant Diffuse Midline Gliomas Is Driven by Disruption of Integrated Metabolic and Epigenetic Pathways doi.org/10.1158/2159-8…
Read the @nytimes story: nytimes.com/2026/07/16/wel…
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Read the study: First-in-human testing of a mutant KRAS vaccine for pancreatic cancer interception in high-risk cohorts doi.org/10.1158/2159-8…
AACR@AACR
In a first-in-human-study published in @CD_AACR, a KRAS-targeting vaccine was safe, elicited durable immune responses, and may help intercept pancreatic cancer in high-risk individuals. Learn more: brnw.ch/21x4b7U
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Now online: The Oncogenic EGFR–SHC1 Fusion Confers Insensitivity to EGFR-TKIs via Dual Activation of N-EGFR Kinase Domain and C-SHC1 Phosphorylation Sites in Lung Cancer doi.org/10.1158/2159-8…
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Now online: Spatial Integration of Protein and Chromosomal States Reveals Early Copy-Number Changes and Genotype-Associated Immune Neighborhoods in Serous Ovarian Cancer Evolution doi.org/10.1158/2159-8…
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Now online: CDK8 Inhibition Releases the Muscle Differentiation Block in Fusion-driven Alveolar Rhabdomyosarcoma doi.org/10.1158/2159-8…
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Now online: CDK8 inhibition induces Mediator trapping and impairment of the EWSR1::FLI1 transcriptional program in Ewing sarcoma. doi.org/10.1158/2159-8…
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Now online: Arachidonic Acid Metabolism in PMN-MDSCs Suppresses Antitumor Capacity of T Cells in KRAS -Mutant Cholangiocarcinoma doi.org/10.1158/2159-8…
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Now online: Senescent Cancer-Associated Fibroblasts Drive Early-Stage Lymph Node Metastasis in Pancreatic Cancer through Lactate-Mediated Metabolic–Epigenetic Rewiring doi.org/10.1158/2159-8…
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Now online: Impact of vitamin D on the colon cancer immune microenvironment: results of a randomized clinical trial of preoperative vitamin D supplementation in patients with stage I-III colon cancer doi.org/10.1158/2159-8…
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News: DNA, Peptide Vaccines Advance Against GBM doi.org/10.1158/2159-8…
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Then, check out the related commentary: C1QL1: A Long-range Signal Orchestrating Glioma Connectivity and Synaptic Remodeling doi.org/10.1158/2159-8…
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Read the latest Editors' Pick: Glioblastoma-Secreted C1QL1 Orchestrates Tumor Microtube Expansion and Neural Synaptic Pruning to Drive Malignant Synapse Formation and Recurrence doi.org/10.1158/2159-8…
AACR@AACR
Studies on targeting neural cross-talk to stop glioblastoma recurrence, a vaccine to prevent colorectal cancer, and other advances were included in the June edition of Editors’ Picks from the AACR journals. Learn more on the AACR Blog: brnw.ch/21x3QAg
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News: Type II JAK2 Inhibitor Gets Off to a Strong Start doi.org/10.1158/2159-8…
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