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Lujan group

Lujan group

@OrgSynLujanLab

Organic Synthesis research group @ CINVESTAV México.

Ciudad De Mexico, Mexico Inscrit le Şubat 2017
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Instituto de Química
Instituto de Química@iquimicaunam·
🧪#ApartaLaFecha para asistir a esta conferencia en el Instituto de Química: 🎙 Prof. Phil S. Baran de @scrippsresearch 🧪 "Simplifying Synthesis with Radical Cross-Coupling" 📅 4 de marzo ⏰ 12 horas 📍 Biblioteca #IQUNAM 🎟 Entrada libre 🏷 Etiqueta a quien pueda interesarse
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Lujan group
Lujan group@OrgSynLujanLab·
@AVazquez1120 Thank you Dr. Andrés Vázquez López for visiting the Department of Chemistry at Cinvestav. Your talk was truly inspiring and motivating for our community. We hope to welcome you back soon!
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Quimica Cinvestav
Quimica Cinvestav@Quim_Cinvestav·
📢PLAZA DE INVESTIGACIÓN Concursa por un puesto para investigador o investigadora de tiempo completo en nuestro departamento. Consulta la convocatoria en: portal.cinvestav.mx/zacatenco/quim…
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Juan Olguin
Juan Olguin@Leolguin·
Si estás interesado en unirte al Departamento de Química del @cinvestav como Profesor investigador, postula a la convocatoria. Esperamos un nuevo colega entusiasta que se una a nuestro reconocido centro de investigación en Ciudad de México. portal.cinvestav.mx/zacatenco/quim…
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Lujan group
Lujan group@OrgSynLujanLab·
@IsaacV_UG @LatinXChem Congrats, Darien! Regarding on the N "ranking" of the ylides, I’m curious how an ylide derived from a sulfinate would rank. Keep up the great work! :)
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Lujan group
Lujan group@OrgSynLujanLab·
@amcscheuer @LatinXChem These are great news! It's fantastic that your method shows no interference with other pesticides/herbicides and can also distinguish other relevant species. Keep up the great work!
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amanda
amanda@amcscheuer·
@OrgSynLujanLab @LatinXChem (2/2) Currently, we are testing with AMPA, a metabolite of glyphosate, which can be distinguished in the colorimetric detection due to the absorption band of the formed product.
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Lujan group
Lujan group@OrgSynLujanLab·
@anahi_frs @LatinXChem Thank you for your reply, América. Keep up the great work, and I look forward to seeing your results once they're published. Regards!
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Alexis Rodríguez
Alexis Rodríguez@alex16rod·
@OrgSynLujanLab @LatinXChem That’s correct. The linear part of the molecule is flat; however, a dihedral angle of 29° is observed for the benzoxazole ring. (3/3)
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Alberto Feliciano
Alberto Feliciano@AlbertoFel87398·
@OrgSynLujanLab @LatinXChem Yes, it’s an interesting exploration over energetic barrier in these kinds of catalysts. However, we keep looking for more active catalysts that can form longer polymer chains with ultra-high molecular weight, which would show better properties (mechanical, thermostable, etc.)
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Lujan group
Lujan group@OrgSynLujanLab·
@anahi_frs @LatinXChem Hello América, this is Armando Luján from Cinvestav MX. Your research is super interesting and highly relevant given the region's agricultural output. How does the activity of your antifungals compare to the agroindustry leaders in treating infections caused by these fungi?
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Quirino Torres Sauret
Quirino Torres Sauret@QuirinoSauret·
@OrgSynLujanLab @LatinXChem Normalmente la chalconas ha presentado actividades farmacológicas de mucho interés, al sustituir los fenilos por hererociclos, creemos que se pueda dar una mejor interacción con las dianas celulares. Para corroborarlo se tiene que realizar estudios in silico.
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Lujan group
Lujan group@OrgSynLujanLab·
@alex16rod @LatinXChem I noticed that in compound 4, the methoxy group (at the top) is orthogonal to the plane, which seems like a local minimum. Did you try making it coplanar with the aryl ring to see if it resulted in a better minimum?
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Lujan group
Lujan group@OrgSynLujanLab·
@alex16rod @LatinXChem Hi Alexis, Armando Luján from Cinvestav MX here. Great molecules! Would extending conjugation via the oxygenated function in the anisole ring be useful? Also, are species 4 and 5 fully planar? (I see some dihedral distortion for the benzoxazole, am I right?
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Lujan group
Lujan group@OrgSynLujanLab·
@AlbertoFel87398 @LatinXChem So, I suppose this isn’t a bad result, right? This would lead to shorter, more tunable polymeric chains, correct? Or were you aiming for more active catalysts?
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Alberto Feliciano
Alberto Feliciano@AlbertoFel87398·
@OrgSynLujanLab @LatinXChem Although catalyst 5a is bulkier than the previously reported Brookhart-type (which favors larger polymer chains), the electronic effects are playing a more significant role. These findings are helping us to design more efficient catalysts for ethylene polymerization.
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Lujan group
Lujan group@OrgSynLujanLab·
@CarlosAngel92 @LatinXChem Hello Carlos, this is Armando Luján from Cinvestav MX. Beyond the general interest in expanding chemical space by combining an amino acid with an indole, is there a specific reason why attaching an indole to the carboxylate end of an amino acid is particularly important?
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