Igor Rudan

A nice weekend in Salzburg, where this year's reception of new members to the European Academy of Sciences and Arts took place. This academy has 37 Nobel Prize winners in its membership and admits the most prominent scientists, artists and experts from all countries of the world.

@UKSimonT @EdinburghUni @MVEP_hr @UKinCroatia Thank you!

On a day that is all about celebrating Croatia’s international recognition 🇭🇷🥳, how fitting to have @ProfIgorRudan from @EdinburghUni 🏴󠁧󠁢󠁳󠁣󠁴󠁿 as guest of honour at tonight’s special event - just one of many Croatians making their mark in 🇬🇧 and the world. Fascinating lecture too!

More than 1,100 research leaders from 77 countries told Nature about where and how they recruit scientists — and who makes the cut. go.nature.com/4040omR

New @Nature The largest study of impact of dietary restriction (DR) in ~1,000 mice with diverse genetic background for health and lifespan nature.com/articles/s4158… —40% caloric restriction had the most lifespan expansion effect but suppressed immune response and loss of lean muscle mass —a divergence of health and longevity effects of DR —"genetic background proved to be the more important factor in determining lifespan."

Once again, the exceptional work by @zalaly and colleagues on impact of Covid for adverse cardiovascular outcomes is independently replicated #LongCovid @NatureMedicine nature.com/articles/s4159…

"I am less interested in the weight and convolutions of Einstein's brain than in the near certainty that people of equal talent have lived and died in cotton fields and sweatshops." ~Stephen Jay Gould Great thread🧵 by @paulnovosad. USA🇺🇸 is also the greatest land of opportunity

The geography of science is changing. As a result, a big push is needed to broaden the pool of scientists eligible to nominate their peers for Nobel prizes go.nature.com/4dKXYfT

Scientists are building giant ‘evidence banks’ to create policies that actually work. @wellcometrust is proud to support this together with @ESRC @UKRI_News, and we will engage other research funders to be a part of this collective nature.com/articles/d4158…

Full text in case you had any difficulties for access (and to read before responding)

Unrelated to Covid, the increasing rates of mortality in the United States. Not seen in any other high income country. jamanetwork.com/journals/jama/… @JAMA_current @shwoolf "Something systemic to the US is limiting survival."

Our review on the prospects of large language models to transform cardiovascular medicine thelancet.com/journals/landi… @GiorgioQuer @ScrippsRTI @scrippsresearch open-access @LancetDigitalH

Major paper! The team found that fibrinogen (which converts to fibrin): -binds to spike -forms clots + neuro issues -acute stage fibrinogen = predictive biomarker of #LongCovid cog dysfunction! -suppresses natural killer (NK) cells (which clear virus!) nature.com/articles/s4158… 1/

This is a remarkable chart. Major reduction in mortality among those taking GLP-1 (i.e. ozempic) vs (statistically) matched group In General: for every 4 ppl not taking GLP-1 who died during 5 yr follow-up, only 1 on GLP-1 died Not randomized control study but very convincing

The threshold for survival in extreme temperatures is lower than we thought — researchers are using state-of-the-art climate chambers to explore when blistering conditions threaten life. go.nature.com/3X3IiiP

The 5 different patterns of brain aging from ~50,000 individuals, with their relationship to lifestyle, genetics and outcomes, derived from MRI and #AI. nature.com/articles/s4159… @NatureMedicine @chrisdav66 and colleagues

The declining number of clinical researchers in the UK is concerning. We at @wellcometrust are working with key partners in the UK to coordinate our clinical training activities more effectively and continue to fund clinical PhD programmes bmj.com/content/386/bm…

How to write a strong discussion section: ⬇️

36% of multinational profits are shifted to tax havens every year. This reduces corporate tax revenue by >$200 billion (10% of global corporate tax receipts). Reallocation would increase domestic profits by 20% in high-tax EU countries, 10% in US, and 5% in developing countries.

A study has found low and middle-income countries in Africa and Asia, that have made the least contribution to the global emission of greenhouse gasses, continue to experience the greatest burden from infectious diseases and the highest vulnerability towards climate change.

"Female health has been historically understudied, with grave consequences for their wellbeing and health equity." A Review in @TheLancetEndo outlines the role of sex steroids on the female brain and on the risk for diseases more prevalent in females: hubs.li/Q02KWjg_0

Athletes from four California universities won 89 Olympic medals. (The United States won 126 total). Athletes from Stanford University alone won more medals than all but seven countries in the world. 🥇🥈🥉