Declan

@ianfsher @talkSPORT Everyone has a value. He’ll get decent money because he sells decent tickets. He can ask for whatever he wants if he believes he deserves that. However he’ll just end up with no fights. And we know what lack of activity does to fighters.

Johnny Fisher was just on @talkSPORT Basically saying he won't get in the ring for low 6 figure payday!! Who the fuck do these clowns think they are!!

@32watto He is incredibly talented however doesn’t show it in an England shirt. He plays well at city as pep has moulded him into what he wants. England don’t play how city play so he’s ineffective. His stats for England back that up

This is a mad take. Foden is what England are crying out for, proper master of the football. English football has a weird way of bringing down their most talented players 😟

Trial dynamics for AVA6103 are so much more interesting than for AVA6000. I.e. #AVCT can dose as much EXd as they want, but unless its release is being sustained, it won’t be effective (as the body excretes EXd so quickly). Successive dose escalations for AVA6103 therefore very likely indicate the sustained release mechanism is effective. That said, this is no longer run by Mr-not-a-clue so they may think RNS’ing DEs looks a little amateur. With respect to adding indications, they would only do that if they were shaking their tail feather but they already have 4(!) which is very punchy for our cash position. AVA6103 is all about utility. I.e. EXd works across so many indications. So if you can prove the breadth across 4/5/6 indications, you’ve proven the investment case. It would also enable AVCT to turn around to the prospective AVA6103 suitors and say you can have breast but we are retaining everything else. Fascinating fortnight ahead.

@stokecity @potterslive_ Strange formation today. If it works great however surely he’s putting pressure on himself

Your Good Friday Potters 📝 ◾️ Bazunu and Lawal return to start ◾️ Cresswell, Seko, Rak-Sakyi and Cissé also in from the outset ◾️ Baker returns to squad for first time since November Team news sponsored by NBe Brokers.

@AndrewDigby3 The good thing is you can buy at 65p and not $10

We should be fucking flying after the little tweet from CC, as RAH has said 100 hours + and no reports of adverse reactions!! Nasdaq we’d be marching towards $10, AIM 65p FFS #AVCT

@AfricaGrowthCap @avacta I’m not expecting any news regarding 6103 at AACR that would be far too soon. PFS in SGC and TNBC Update would be great though along with Regulatory update for the icing on the cake. I’d welcome any kind of comment like that though.

@Decscfc1990 @avacta Just imagine that at AACR in April, CC can state categorically that none of the "X" patients dosed with AVA6103 have suffered any major adverse side effects, and are continuing with the treatment! Viva la Beast! #avct

#AVCT A great update today from @avacta. Moving along nicely now. Plenty of news to come with AACR in April, hopefully updates on 6k in SGC and TNBC. So much to look forward to until year end. It should be a completely different AGM this year to last years.

@BoxingMassacre @WeAreTheOverlap Sport is ruthless. Eddie backed him only because he seen the £ signs. He backed him for doping at the same time as hammering others for doping. Remember miller… Connor’s chasing the money if he loses his next couple he becomes irrelevant and doesn’t get paid well.

Conor Benn says his loyalty NOT with Matchroom and anyone can say what they want about him he says his dad approved the decision to chase the 💰 as who will pay his mortgage when he retires. He said if lost the next 3 fights he’d be lucky to get a ringside seat @WeAreTheOverlap

@SteveSpevack Yeah it’s too far. I like Allen and I think it’s a great money fight for him. However hrgovic could permanently hurt him. Allen can take punishment with a solid chin however that will catch up with him.

We all love Allen… but is Hrgovic a step too far? 🤔

@TragedyCalls @tom_the_bomb__ I did pick up on this when I first read it. CC knows what she’s doing with that language.

@tom_the_bomb__ They did not use the term 'dosed'. They used the team 'treated'. Seems sensible to align language - particularly h err

From today, #AVCT is no longer a single asset clinical-stage biotech. First patient dosed with one of the most potent TOP1 inhibitors out there. The market says that’s worth +0.97%. I wonder what pharma think it's worth.

@NoSmokeBoxing The annoying thing for me is Ian’s could easily go and fight wardley or Dubois next. However whilst he’s making money keep taking these average fighters on the way up. Can’t wait to watch him in one of these big stadium fights.

🚨 Ben Davison says finding Moses Itauma's next opponent is proving difficult after the 21-year-old's fifth-round stoppage of Jermaine Franklin - a result that puts established heavyweights in a high-risk, low-reward situation.

Itauma is a beast!!!

@tonywestonuk @Unv3rifiedTom @Heccles94 Of course there is. You sound so bitter that people have done well and enjoy it. The idea any person would want someone taxed to the tune of 80% is crazy.

@Decscfc1990 @Unv3rifiedTom @Heccles94 When you hit 500k today, there is no point in working. Because your existing wealth carries on generating money for you without you doing anything at all. And many millionares live like this...doing nothing, but enjoying the income.

I think we should change the tax brackets. Up to 15k tax free Basic rate 20% up to 60k 60k - 80k - 30% 80k - 150k 40% 150k - 500k - 50% 500k - 2,000,000 55% Then 60% on the rest over 2,000,000 What do you think?

@tonywestonuk @Unv3rifiedTom @Heccles94 I find it scary that the average British citizen is completely obsessed with taxing people. I get why the government want to do it. I never get why any normal person wants to hammer people with tax.

@tonywestonuk @Unv3rifiedTom @Heccles94 Because once you hit 500k there would be no point in working. Why keep hammering people who do well to give it to people who can’t be arsed to work. What we need is corporations to pay the correct tax and get half the jobless bums who don’t work back in work.

@Heccles94 I think your completely off your head

@Mike182035 @gilesgeddes Mike I’ve always wondered why cc chose exetecan for 6207. Surely no one would want 6103 without the 6207?

@gilesgeddes #AVCT Small 6207 preclinical partnership co-dev deal in May provides the missing £10m imo For me it's vital it's 50/50 co-dev as this sets the template for all future deals Makes us a Seagen rather than an also ran - our science team and frugality makes this possible GLA

As I’ve tweeted consistently over the last few months, I am very happy with this strategy of a small placing (smaller than I expected) to get us through 6k P1b and initial P1 6103 results. Great to see the director buys as well. #AVCT.

@111BEN_111 The good thing about the raise is the timing. For once they haven’t waited until the last moment in desperate need. This tops us up before the decline started.

#AVCT While not entirely unexpected as we cleared through March, it became an increasing necessity to finance. I personally had a target of ~70p for a fundraise. Since October, following the last raise, every news piece (SGC data, FDA clearance, removal of limits, etc.) now appears to have been effectively priced at zero. The calibre of those who participated will decide the quality, but ultimately this is, in my view, the bare minimum mgmt should be doing. This should not be lauded as an accomplishment; only a few months ago we were effectively in the same position, waiting for the next inflection point, and I am sure many would have been disappointed had this been the outcome presented at the time. It’s nice to see financial commitment from SOME directors 👏, and in my view it remains a good buy with multiple pieces of news flow imminent, now financially sound. I remain confident a deal will land in the coming months as a prerequisite to moving programmes forward. Patient shareholders have patiently carried extraordinary risk for years, it’s very much time that risk is NOW monetised. The jury is now in session…

@lauraellison18 @Nike The genuine tops are unfortunately made in the same factories. And actually are worse as they receive less per unit than the lights of DHgate.

It’s my little boys first World Cup, to buy a baby kit that will fit him for 6 months max is £54.99!! That’s absurd, pricing people out of hobby @Nike ☹️