Declan

@AfricaGrowthCap @avacta I’m not expecting any news regarding 6103 at AACR that would be far too soon. PFS in SGC and TNBC Update would be great though along with Regulatory update for the icing on the cake. I’d welcome any kind of comment like that though.

@Decscfc1990 @avacta Just imagine that at AACR in April, CC can state categorically that none of the "X" patients dosed with AVA6103 have suffered any major adverse side effects, and are continuing with the treatment! Viva la Beast! #avct

#AVCT A great update today from @avacta. Moving along nicely now. Plenty of news to come with AACR in April, hopefully updates on 6k in SGC and TNBC. So much to look forward to until year end. It should be a completely different AGM this year to last years.

@BoxingMassacre @WeAreTheOverlap Sport is ruthless. Eddie backed him only because he seen the £ signs. He backed him for doping at the same time as hammering others for doping. Remember miller… Connor’s chasing the money if he loses his next couple he becomes irrelevant and doesn’t get paid well.

Conor Benn says his loyalty NOT with Matchroom and anyone can say what they want about him he says his dad approved the decision to chase the 💰 as who will pay his mortgage when he retires. He said if lost the next 3 fights he’d be lucky to get a ringside seat @WeAreTheOverlap

@SteveSpevack Yeah it’s too far. I like Allen and I think it’s a great money fight for him. However hrgovic could permanently hurt him. Allen can take punishment with a solid chin however that will catch up with him.

We all love Allen… but is Hrgovic a step too far? 🤔

@TragedyCalls @tom_the_bomb__ I did pick up on this when I first read it. CC knows what she’s doing with that language.

@tom_the_bomb__ They did not use the term 'dosed'. They used the team 'treated'. Seems sensible to align language - particularly h err

From today, #AVCT is no longer a single asset clinical-stage biotech. First patient dosed with one of the most potent TOP1 inhibitors out there. The market says that’s worth +0.97%. I wonder what pharma think it's worth.

@NoSmokeBoxing The annoying thing for me is Ian’s could easily go and fight wardley or Dubois next. However whilst he’s making money keep taking these average fighters on the way up. Can’t wait to watch him in one of these big stadium fights.

🚨 Ben Davison says finding Moses Itauma's next opponent is proving difficult after the 21-year-old's fifth-round stoppage of Jermaine Franklin - a result that puts established heavyweights in a high-risk, low-reward situation.

Itauma is a beast!!!

@tonywestonuk @Unv3rifiedTom @Heccles94 Of course there is. You sound so bitter that people have done well and enjoy it. The idea any person would want someone taxed to the tune of 80% is crazy.

@Decscfc1990 @Unv3rifiedTom @Heccles94 When you hit 500k today, there is no point in working. Because your existing wealth carries on generating money for you without you doing anything at all. And many millionares live like this...doing nothing, but enjoying the income.

I think we should change the tax brackets. Up to 15k tax free Basic rate 20% up to 60k 60k - 80k - 30% 80k - 150k 40% 150k - 500k - 50% 500k - 2,000,000 55% Then 60% on the rest over 2,000,000 What do you think?

@tonywestonuk @Unv3rifiedTom @Heccles94 I find it scary that the average British citizen is completely obsessed with taxing people. I get why the government want to do it. I never get why any normal person wants to hammer people with tax.

@tonywestonuk @Unv3rifiedTom @Heccles94 Because once you hit 500k there would be no point in working. Why keep hammering people who do well to give it to people who can’t be arsed to work. What we need is corporations to pay the correct tax and get half the jobless bums who don’t work back in work.

@Heccles94 I think your completely off your head

@Mike182035 @gilesgeddes Mike I’ve always wondered why cc chose exetecan for 6207. Surely no one would want 6103 without the 6207?

@gilesgeddes #AVCT Small 6207 preclinical partnership co-dev deal in May provides the missing £10m imo For me it's vital it's 50/50 co-dev as this sets the template for all future deals Makes us a Seagen rather than an also ran - our science team and frugality makes this possible GLA

As I’ve tweeted consistently over the last few months, I am very happy with this strategy of a small placing (smaller than I expected) to get us through 6k P1b and initial P1 6103 results. Great to see the director buys as well. #AVCT.

@111BEN_111 The good thing about the raise is the timing. For once they haven’t waited until the last moment in desperate need. This tops us up before the decline started.

#AVCT While not entirely unexpected as we cleared through March, it became an increasing necessity to finance. I personally had a target of ~70p for a fundraise. Since October, following the last raise, every news piece (SGC data, FDA clearance, removal of limits, etc.) now appears to have been effectively priced at zero. The calibre of those who participated will decide the quality, but ultimately this is, in my view, the bare minimum mgmt should be doing. This should not be lauded as an accomplishment; only a few months ago we were effectively in the same position, waiting for the next inflection point, and I am sure many would have been disappointed had this been the outcome presented at the time. It’s nice to see financial commitment from SOME directors 👏, and in my view it remains a good buy with multiple pieces of news flow imminent, now financially sound. I remain confident a deal will land in the coming months as a prerequisite to moving programmes forward. Patient shareholders have patiently carried extraordinary risk for years, it’s very much time that risk is NOW monetised. The jury is now in session…

@lauraellison18 @Nike The genuine tops are unfortunately made in the same factories. And actually are worse as they receive less per unit than the lights of DHgate.

It’s my little boys first World Cup, to buy a baby kit that will fit him for 6 months max is £54.99!! That’s absurd, pricing people out of hobby @Nike ☹️

@TheBoxingMan_ I also love the fact how much he puts his ego aside to learn from Usyk. Extremely impressive

No coke binge, no gaining weight, no exile for 2 years. Special people can rise through adversity, take responsibility and push forward! 🥊

@EPLBible No it’s character. It’s what people pay to see.

🚨 DEBATE - Was this disrespectful from Cherki? 🧐

@Jamie_Hodder21 @Reading106 I don’t realise unless it’s you football league home club why anyone would purchase a genuine top anymore. I can get both my kids kitted out for $20 dollars for the full kit. Or I can pay 55-60 for one of them to have a top. It’s a joke.

And the big wigs at Nike and co wonder why people pay for “knock off” versions? I know it’s an old debate and shirts have been this price for ages but it’s just out of order.

@KirraneJam60371 @avacta Charting the current of innovation and opportunity in oncology 23 Mar, 14:30

@Decscfc1990 @avacta Are they actually going to Lisbon? It was posted and taken down almost immediately.

#AVCT another busy week for CC this week, this time in Lisbon 🇵🇹. Can’t ask anymore from CC and team @avacta at the moment. 🙌 The market will recognise it….. one day.

@KirraneJam60371 @avacta