Endocrine Pathology

Interesting #EndoPath data? Send us your article! Fast turn around & expert reviewers! Make our journal your voice! link.springer.com/journal/12022

Research published in @EndoPath presents genetic insights from adrenal tumors in a MEN1 patient. The study identifies mutations in TP53 and NF1 linked to malignancy, raising awareness of increased cancer risk in MEN1 patients. bit.ly/3N26OyS

Whole-exome sequencing of adrenal tumors from a MEN1 patient reveals shared mutations between adenoma and carcinoma, suggesting a possible biological link - read it here: link.springer.com/article/10.100…

RAS mutations are common in thyroid nodules, but what do they mean clinically? In 354 nodules, isolated RAS was often linked to benign/low-risk lesions, while RAS + additional mutations (e.g., EIF1AX, TERT) significantly increased tumor aggressiveness. link.springer.com/article/10.100…

Peer review is the foundation of high-quality pathology research. We thank the reviewers recognized in this issue of Endocrine Pathology for their expertise, rigor, and commitment to advancing the field. Your work strengthens every paper we publish. 🔬 link.springer.com/article/10.100…

Pediatric adrenocortical carcinoma is not just “small adult ACC.” Different biology, different prognosis - and major therapeutic consequences for children. This review highlights why accurate pathologic assessment matters more than ever! link.springer.com/article/10.100…

Can histoarchitecture predict genotype in paragangliomas? In this study of 104 PGLs, AI-based analysis of reticulin architecture accurately predicted germline cluster 1 status, bridging histopathology and molecular classification. Read more: link.springer.com/article/10.100…

New article highlight! EBV-positive neuroendocrine carcinoma of the nasopharynx shows a distinct, high-TMB genomic profile with potentially actionable alterations - supporting recognition as a unique disease entity. link.springer.com/article/10.100…

🔬New in Endocrine Pathology! Proteomic analysis of bilateral macronodular adrenocortical disease, a rare cause of Cushing syndrome, identifies 3 distinct protein patterns linked to pathology and genetics - opening new diagnostic perspectives. link.springer.com/article/10.100…

@EndoPath reports on EBV-positive neuroendocrine carcinoma of the nasopharynx, a rare cancer with distinct molecular features. Whole-exome sequencing reveals high mutational burden and key mutations in TP53, APC, and PROK2. bit.ly/4sXLF8W

New in Endocrine Pathology! A fascinating case of a non-invasive follicular cell-derived spindle cell thyroid neoplasm with an NRAS p.Q61R mutation - expanding what we think we know about thyroid tumors! 👩🏻‍⚕️👨🏻‍⚕️ Read more ➡️ link.springer.com/article/10.100… #PathTwitter

A study in @EndoPath analyzes protein signatures in bilateral macronodular adrenocortical disease (BMAD) using LC-MS/MS. Findings reveal three distinct proteomic groups linked to microscopic and molecular characteristics. bit.ly/3ZeR51G

🧬 New research in our journal! Mismatch repair (MMR) deficiency is rare (2.2%) in pituitary neuroendocrine tumors, but reduced MMR expression is seen in specific aggressive subtypes - especially functioning corticotroph and invasive lactotroph tumors. link.springer.com/article/10.100…

A new study compares focus quality across three whole-slide scanners for thyroid cytology! An automated Laplacian variance score helped detect out-of-focus areas, especially in 3-D cell clusters, and may support scanner choice and quality control. link.springer.com/article/10.100…

The Endocrine Pathology Society is honored to present the 2025 Lifetime Achievement Award to Dr. Arthur S. Tischler 🎉 A pioneer in PPGL pathology whose decades of discoveries, models & mentorship shaped the field. Read more in our latest article! link.springer.com/article/10.100…

A study in @EndoPath details an adult male with a retroperitoneal mass. Biopsy revealed atypical epithelial cells and aberrant β-catenin expression, leading to a diagnosis of pancreatoblastoma despite absent squamoid nests. bit.ly/3Y26ulp

A multicenter study in @EndoPath analyzed 119 cases of medullary thyroid carcinoma (MTC) and found DLL3 expression in 89.1% of tumors, with high levels linked to larger size and aggressive features. bit.ly/4oRKtR7