Jon Brown Lab me-retweet
Happy Thanksgiving 🦃🍁🍽 from this rockstar @VUMCMedicineRes @VUMC_Medicine team! Grateful to get to work alongside these amazing doctors. #WomenInMedicine Thx to all #healthcareworkers serving today!
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Jon Brown Lab
48 posts
Jon Brown Lab
@JonBrownLab
Twitter for the Jon Brown Lab, located in the division of cardiovascular medicine at Vanderbilt University Medical Center. @VUMChealth 🧬 ⚓️
Nashville, TN Bergabung Nisan 2020
244 Mengikuti131 Pengikut
Jon Brown Lab me-retweet
Congrats to Ronan Bracken graduate student in @JonBrownLab. Advancing to PhD candidacy in @VandyBiochem. #donewithquals!!! 🙌🧬🧬🧬
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@JonathanBrownMD @VandyBiochem So proud of Ronan! Excellent work 🎉
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Jon Brown Lab me-retweet
Join us in welcoming our new #TechnicalEditor @CircRes Dr. Amanda Doran MD PhD from the Division of Cardiology @VUMC_heart. Her research focuses on the role of innate immunity and #inflammation resolution in #atherosclerosis. Congratulations! @AmandaDoranLab
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Jon Brown Lab me-retweet
Big congrats to outstanding colleague & "Cardio-Immunologist" extraordinaire! & fellow PRB3 "neighbor" (well...until a few months ago)! @VUMChealth @VUMC_heart @AmandaDoranLab @JonathanBrownMD @JonBrownLab @JaneFreedmanMD @CircRes @AHA_Research @annetkiraboc1 @nhpetunia
Circulation Research@CircRes
Join us in welcoming our new #TechnicalEditor @CircRes Dr. Amanda Doran MD PhD from the Division of Cardiology @VUMC_heart. Her research focuses on the role of innate immunity and #inflammation resolution in #atherosclerosis. Congratulations! @AmandaDoranLab
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Jon Brown Lab me-retweet
Our recent publication was reviewed in NEJM today! @davidrliu, @NIHDirector, @JonBrownLabVUMC, @Progeria, @mrrerdos The figure is absolutely killer!
Will definitely be sending this to my mom.
nejm.org/doi/full/10.10…
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Jon Brown Lab me-retweet
Excited to have Dr. Mac Linton present at @VUMChealth CV Research Series. Terrific colleague, scientist & even better hogfish cook & host! @JaneFreedmanMD @KathrynMooreLab @merrymanlab @alan_daugherty @JoshuaBeckmanMD @VAgrawalMDPhD
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Jon Brown Lab me-retweet
Read this study from Paul Cohen @RockefellerUniv about Brown Fat in humans and risk of cardiometabolic disease. Nice to see independent work from former @BrighamFellows. nature.com/articles/s4159…
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Jon Brown Lab me-retweet
The findings of a study in Nature demonstrate the potential of in vivo base editing as a possible treatment for Hutchinson–Gilford progeria syndrome and other genetic diseases by directly correcting their root cause. go.nature.com/38ktlQ1
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Jon Brown Lab me-retweet
News & Views: No cure exists for the lethal premature-ageing condition Hutchinson–Gilford progeria. A gene-editing tool offers a way to treat the condition in mice, according to a Nature paper. Could this approach lead to an effective therapy? go.nature.com/3oom0EJ
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Jon Brown Lab me-retweet
In vivo base editing shows promise in treating the genetic accelerated-aging disorder Hutchinson–Gilford progeria syndrome in mice - find out more in our latest highlight of research by @jonbrownlabVUMC
@davidrliu @LiuGroup et al. go.nature.com/3igjwpJ
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Jon Brown Lab me-retweet
Research from the @JonBrownLabVUMC and collaborators have rescued mice afflicted with progeria—accelerated aging—which could lead to a cure for Hutchinson-Gilford progeria syndrome in humans.
news.vumc.org/2021/01/06/gen…
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Jon Brown Lab me-retweet
Congratulations to @SarnoffCardio & @BrighamFellows alumnus/current @VUMChealth cardiologist Dr. John Brown. Really nice story & demonstrating power of teamwork. Can studying progeria provide insights into CV aging? @JonBrownLabVUMC @saptarsi_haldar @tmmichelangelo @Progeria
Jonathan Brown@JonathanBrownMD
So proud of this work demonstrating DNA base editing treatment for #progeria in human cells & mouse model. Amazing collaborative team @davidrliu @NIHDirector @LukeKoblan & Mike Erdos at NIH and my @VUMCResearch team @lindsaymdavison & Sean Doherty rdcu.be/cc90j
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Jon Brown Lab me-retweet
Great science marches on.
A rare incurable disease—progeria—tackled by #CRISPR genome editing with striking results in mouse model
nature.com/articles/s4158…
@nature @davidrliu @NIHDirector @LukeKoblan @JonBrownLabVUMC
David's ★🧵👇
twitter.com/davidrliu/stat…
David R. Liu@davidrliu
Today we report the use of base editing in patient-derived cells and in mice to correct the most common cause of progeria, the devastating rapid aging disease. Progeria is typically caused by a dominant negative C•G-to-T•A point mutation in LMNA. 1/11 drive.google.com/file/d/1oH4W0z…
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Jon Brown Lab me-retweet
Jon Brown Lab me-retweet
So proud of this work demonstrating DNA base editing treatment for #progeria in human cells & mouse model. Amazing collaborative team @davidrliu @NIHDirector @LukeKoblan & Mike Erdos at NIH and my @VUMCResearch team @lindsaymdavison & Sean Doherty
rdcu.be/cc90j
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Jon Brown Lab me-retweet
Here is a really great article about our progeria work that mentions the early days where we only had DNA editing data from only a single LMNA c.1824 C>T mouse– @davidrliu, @JonBrownLabVUMC, and @NIHDirector may remember fondly! Check it out here: statnews.com/2021/01/06/cri…
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Jon Brown Lab me-retweet
Today we report the use of base editing in patient-derived cells and in mice to correct the most common cause of progeria, the devastating rapid aging disease. Progeria is typically caused by a dominant negative C•G-to-T•A point mutation in LMNA. 1/11 drive.google.com/file/d/1oH4W0z…
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