Piali Sengupta

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Piali Sengupta

Piali Sengupta

@SenguptaLab

Brandeis Bio/Neuro. We study multiple aspects of sensory biology. Mostly in worms. Lab appears to be powered by vast quantities of junk food. Opinions mine.

Waltham, MA, USA Bergabung Ağustos 2010
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Piali Sengupta
Piali Sengupta@SenguptaLab·
Multiple postdocs out to academic/industry jobs + 2 grant NOAs in = open postdoc position. Worms are great to work with, sensory biology is an endlessly fascinating topic, and we are a group of good humans. Please email if interested!
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Piali Sengupta
Piali Sengupta@SenguptaLab·
Opening for a lab manager/Res Asst! This is a great position if you want more research experience (& perhaps co-author a paper or two!) before heading to grad school. We are a sociable, supportive, inclusive, and dynamic group - come join us. brandeis.wd5.myworkdayjobs.com/Jobs/job/Brand…
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Piali Sengupta
Piali Sengupta@SenguptaLab·
🎉👏🏽Check out the brand new lab of our star (and much missed) ex-postdoc @nathanCSharris!!! He has a super cool planned research program and is going to be an awesome mentor. Go Nathan!!
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Piali Sengupta
Piali Sengupta@SenguptaLab·
Multiple postdocs out to academic/industry jobs + 2 grant NOAs in = open postdoc position. Worms are great to work with, sensory biology is an endlessly fascinating topic, and we are a group of good humans. Please email if interested!
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Piali Sengupta
Piali Sengupta@SenguptaLab·
@Roy_Lab_Thinks Mine too. Had no idea of the history - (wrongly) thought it had Indian origins. Fascinating.
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Semil Choksi
Semil Choksi@semilc·
We thought there wasn't much new to learn about the cell cycle. Turns out we were wrong! Our paper (out today @Nature) identifies a novel alternative cell cycle that regulates differentiation, not cell division. tinyurl.com/4a6yeuke. 1/10
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Piali Sengupta
Piali Sengupta@SenguptaLab·
Alison used a ts kinesin allele that she generated (thanks to Chlamy ts screens!) to show that a) IFT is not necessary to maintain cilia of the AWA olfactory neurons, & b) even w/o cilia, AWA can respond to some food-related odorants. 2/6
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Moe Mahjoub 🇨🇦🍁
Moe Mahjoub 🇨🇦🍁@MahjoubLab·
Not sure what to say. I knew the day was coming, but still not ready. How do you acknowledge a man that made your whole life possible? Go hug your loved ones, you might not get another chance. Rest in peace, Baba. I’ll see you again sometime, somewhere 💔
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Piali Sengupta
Piali Sengupta@SenguptaLab·
TL;DR: IFT & cilia structure shape responses to stimuli sensed by a single neuron type in different & unexpected ways. Alison untangles this complexity by conditionally manipulating IFT & measuring response dynamics to individual chemicals. Questions/comments welcome! 6/6
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Piali Sengupta
Piali Sengupta@SenguptaLab·
What about sensory response adaptation? By acute manipulation of IFT, Alison shows that IFT is needed for diacetyl but not pyrazine adaptation, likely by trafficking the diacetyl but not the pyrazine receptor. 5/6
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Piali Sengupta
Piali Sengupta@SenguptaLab·
🎉New lab preprint! 🔥🔥work by super postdoc @alison_marie1. C. elegans sensory neurons have gorgeous #cilia at their dendrite ends. We’ve always thought that a) no cilia = no sensory responses, & b) no IFT = no cilia. Punchline is we thought wrong. Read on for more. 1/6
bioRxiv@biorxivpreprint

Differential modulation of sensory response dynamics by cilia structure and intraflagellar transport within and across chemosensory neurons biorxiv.org/cgi/content/sh… #bioRxiv

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Piali Sengupta
Piali Sengupta@SenguptaLab·
Popping back on here to thank my mentors, colleagues and friends @BrandeisScience & elsewhere, my funders, & my very patient family. Most importantly, thank you to all the students & postdocs who chose to science along with me. And of course 🙏🏽 to our beloved worms!
American Academy of Arts & Sciences@americanacad

Announcing our new members! The Academy is honoring excellence in an array of disciplines and professions, and inviting these new members to join our work to advance the common good. The first members were elected in 1781. Learn who was elected in 2024: amacad.org/news

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