Ruth V. Nichols & Brendan L. O'Connell

It's been a while, but we published sciMETv3 in @CellGenomics in the beginning of this year!! cell.com/cell-genomics/…

Single-cell DNA methylation analysis tool Amethyst reveals distinct noncanonical methylation patterns in human glial cells biorxiv.org/cgi/content/sh… #biorxiv_neursci

Our daughter's latest artwork: "Science Kitty"

Very excited that @acadey80 presented on sciMETv3 at #AGBT24 ! I am very proud to say that I (Ruth) am the lead on this :)

This new kit is based off our protocol!

New preprint! sciMET-cap, where we use hybrid capture to reduce the sequencing burden of scMethylation and show ~6,000 cell preps are possible using a benchtop sequencer! Led by S. Acharya and @oconnellphds with @DrTedPBraun & @L_Rylaarsdam. biorxiv.org/content/10.110…

Summary of our latest two papers on GenomeWeb! Thanks for the coverage - we are excited about both of these techniques regarding how they can improve the scale of single-cell epigenomic studies; both led by @oconnellphds! @OHSUSOM #singlecell #epigenetics

Excited to have our work using the @TakaraBioUSA iCell8 instrument with single-cell combinatorial indexing to achieve high-throughput scATAC out in early access in @genomeresearch led by @oconnellphds! #singlecell @OHSUSOM @OHSUNews @OHSUBrain (1/4) genome.cshlp.org/content/early/…

A high-throughput method for generating single-cell DNA methylomes with high coverage @acadey80 @oconnellphds go.nature.com/3WsKkGl

Super excited to have our paper out today! Went from the first experiment to an accepted paper in 1 year!

@love_dalen The sequencing adapters on the molecule ends are like the covers of the books. Lots of books (reads) in the library. 🤷

Are there any scientists left here on Twitter? I have a question! Why is a genomic library (sequencing library) called a library? In what way does this have similarity to a library full of books?

Ice machine's set to ottermatic

@marissacoconut It was written in the 60s before Sci-Fi was a major genre.. so the fact it has any 'sci-fi names' is saying something

@OregonZoo has the best content on Twitter by far

@marissacoconut Rancher

New paper from our lab is out today! Brendan is a co-author. He worked on the s3-GCC portion

Cub in a tub

Happy fifth birthday to Maple! Her team threw a party with branches, otters and Filbert, who took a cookie to go.

Interested in single-cell genomics but need help keeping up with a rapidly changing field? Check out our free #singlecellgenomicsday workshop, starting in a few minutes! Full agenda and livestream at satijalab.org/scgd, or follow along below: youtube.com/watch?v=lX4d12…