固定されたツイート
Happy to contribute along with many other colleagues to the 2 Kidney papers bridging @KPMProject and @_hubmap that are just out today in @Nature and @NatureComms :
nature.com/articles/s4158…
nature.com/articles/s4146…
English
Tarek M. Ashkar (El-Achkar)
723 posts
Tarek M. Ashkar (El-Achkar)
@AshkarLab
Physician Scientist, Nephrologist. Interests: #AKI, #Uromodulin, Multiplex imaging & Spatial analytics, Immune mediated kidney injury. Investigator @KPMProject
Indiana, USA 参加日 Mayıs 2017
497 フォロー中655 フォロワー
Tarek M. Ashkar (El-Achkar) がリツイート
Kidney casts contain high levels of PROM1, a marker linked to cell damage and dedifferentiation based upon new #ASNCJASN study. kidney.pub/CJASN0982
English
Registration link
iu.zoom.us/webinar/regist…
Preliminary agenda
nam12.safelinks.protection.outlook.com/?url=https%3A%…
Tarek M. Ashkar (El-Achkar)@AshkarLab
Save the Dates: May 20 & 21, 2026 The Indiana O’Brien Center for Advanced Renal Microscopy will host a virtual workshop on Spatial Protein Imaging. Details coming soon on the program and registration (free). Stay tuned!!
English
Save the Dates: May 20 & 21, 2026
The Indiana O’Brien Center for Advanced Renal Microscopy will host a virtual workshop on Spatial Protein Imaging. Details coming soon on the program and registration (free). Stay tuned!!
English
@Carmendemigue12 @KidneyInCVD Thank you so much Carmen! So kind of you. Big kudos to all the team, but especially Azuma Nanamatsu who has been the driving force behind this work.
English
English
What proteins do kidney tubular casts contain? More than what you think but with notable absences. New in CJASN journals.lww.com/cjasn/abstract…
English
The secret of youth: posting a profile picture on the university website. Diamonds are forever.
English
Tarek M. Ashkar (El-Achkar) がリツイート
‘‘Tis always the season for Uromodulin
NKF Nephrology Professionals@NKF_NephPros
❄️🎄 On the First Day of Continuing Education, NKF gave to me… a new episode exploring uromodulin. Dr. Gaddy. LaFavers, and Garimella explore uromodulin's role in infection defense, AKI, and kidney stress. bit.ly/3DamjQ9 @klafavers @pranavgarimella @AnnaGaddy
English
Times have changed. Reviewing papers stopped being predominantly a duty and an academic privilege, to also becoming an integral part of a multi-billion dollar publishing industry. Compensate reviewers? Any other examples of industry sustained by free work?
English
The Role of the Vascular Niche in Regulating Kidney Tubulo-Interstitial Fibrosis - Kidney International kidney-international.org/article/S0085-…
English
This perspective in @asnpublications CJASN discusses the importance of spatial biology in studying kidney disease and the translational implications to identify therapeutic targets and biomarkers. journals.lww.com/cjasn/citation…
English
Happy to contribute to this superb work!
ASN Publications@asnpublications
The lymphatic system has historically been understudied due to the difficulty of distinguishing it from the blood vasculature. This #ASNKidney360 paper's authors optimized an antibody-based method for imaging hard-to-visualize adult murine kidney lymphatics. Read more: kidney.pub/KID0919
English
Linking histology with Omics. Happy to contribute to this work that offers a really nice tool. @_hubmap nature.com/articles/s4146…
English
Kudos to all the team @IUKidney and all the collaborators and especially the participant heroes from @KPMProject who made this work possible
IU School of Medicine@IUMedSchool
Kidney diseases are a leading cause of death in the U.S. They affect 14% of adults, often without knowing it. IU researchers are mapping kidney cell types to improve diagnosis and open the door to more precise therapies. bit.ly/47HwKHE
English
@ivivek87 Thanks! Yes, there were intermediary states THY1+, PROM1+(and VCAM1+), but loss of THY1 and persistence of PROM1 seems to correlate with injury and maladaptive repair.
English
@AshkarLab Congratulations! PROM1 has always been a bit double edged sword. Really interesting to see this.
English
Our latest in @ScienceAdvances from a large collaboration through @KPMProject . We characterize a population of PTs in human kidney that express the regenerative marker THY1. THY1+ PTs are lost in kidney disease science.org/doi/10.1126/sc…
English
Tarek M. Ashkar (El-Achkar) がリツイート
Kidney cells can protect themselves during injury, but the mechanisms were unclear.
ASCI member Tarek M. El-Achkar @AshkarLab & team @IUMedSchool now show that oxidative stress induces an isoform of uromodulin that re-routes to the mitochondria to enhance energy production.
View paper: jci.org/articles/view/…
English
Very nice excited to see this work published and also the super well done editorial by @Vishal_D_Patel
Journal of Clinical Investigation@jclinicalinvest
Kidney cells can protect themselves during injury, but the mechanisms were unclear. @AshkarLab & team @IUMedSchool now show oxidative stress induces an isoform of uromodulin that re-routes to the mitochondria to enhance energy production. View paper: jci.org/articles/view/…
English
Looking forward to this tomorrow!
Leica Microsystems@LeicaMicro
How do trillions of cells work together to form & maintain the human body? @AshkarLab & @sarahteichmann1 will guide you through 3D & 4D spatial imaging, uncovering how organs function, develop, & respond to disease. Join the discussion! fcld.ly/hyh0vuq #CellMapCrew
English