BarabanLab
2.6K posts

BarabanLab
@BarabanLab
Translational epilepsy research in an academic setting | neuroscience, drug discovery, zebrafish, electrophysiology, cell therapy, precision medicine and more
San Francisco, CA 参加日 Mayıs 2013
3K フォロー中2.9K フォロワー
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@LifeCanvasTech Link to Progress in Neurobiology publication: sciencedirect.com/science/articl…
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In order to visualize MGE progenitor cell migration, the authors used LifeCanvas whole-brain mapping. This #SmartSPIM video shows extensive spread of GFP+ cells derived from MGE progenitors 60 days post-transplantation. Read the paper: bit.ly/4bNm0tB (4/4)
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This #FluorescenceFriday comes from the @BarabanLab at UCSF: a new paper by @joseanemarafiga et al. sheds light on how dysregulation in the C1qa gene, which has been linked to neurological disorders like #epilepsy, affects inhibitory neural circuits. (1/4) 🧵
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@Nature @BarabanLab Excuse the interruption. How’s Cronutt doing these days. An update?
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A researchers’ propensity for risky projects is passed down to their doctoral students — and stays with trainees after they leave the laboratory
go.nature.com/4qpoyCD
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@markbothwell @JoyceCarolOates Sounds eerily close to the plot of an Ayn Rand novel I read a long time ago.
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@JoyceCarolOates My fantasy is that everyone with intelligence departs the country, leaving the illiterate, racist, and technologically challenged MAGA masses to muddle on in poverty and disease.
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oh, no one's going. these are just wishful fantasies.
LaughAtAllOfThem@kmsitall
@JoyceCarolOates Yeh, this is the problem… all you folks picking up and leaving — leaving us to clean up your shit. It’s a cowardly act for those who are privileged to run off to a safe haven somewhere and watch from afar as your own country burns.
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@NeurosurgUCSF @Cronutt1 @sixflagsDK @UCSF @Claire_Simeone @UCI_EpiCenter Our favorite sea lion living seizure free! @curedravet @AmEpilepsySoc @curestxbp1 @EpilepsyInst @CureEpilepsy @UCI_EpiCenter @UCSF
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More than five years later, @Cronutt1 is still seizure-free and living his best life @sixflagsDK after receiving an experimental therapy with transplanted interneuron progenitor cells developed by the @BarabanLab: youtu.be/hZpFH5J5lbo
@UCSF @Claire_Simeone @UCI_EpiCenter

YouTube
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The 2020 chemistry laureate Emmanuelle Charpentier shares her best career advice to the next generation of scientists:
"The general advice I give is always to listen to oneself. It’s important to listen to oneself and follow the gut feeling, follow the intuition. In research, it is really important to follow what one likes to do. I liked different topics, and it was difficult to choose. But I think what helps a lot is just to enjoy the science and to see what the science can bring. Focus on this and really trigger the trust in oneself, the sense of curiosity of what we like to do and the joy of the science. This is important because it allows you to deal with the rest. So, they have to learn all these aspects, to see that the rest is little steps that may not work perfectly, but that, at the end of the day, make the beauty of this work. We are very privileged to be able to ask questions and work on what we like to work with."
Read our full interview with Charpentier: nobelprize.org/prizes/chemist…

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About 0.1 percent of the global population, some 8.8 million people, identifies as scientists, which means only a small fraction of people personally know a scientist. sciencenews.org/article/scient…
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Would be perhaps useful to point out that neural organoids are not miniature brains and that they model fetal stages of parts of the human brain during development (rather than aging or rejuvenation). At these stages, especially in cortical organoids, neural activity is largely driven by spontaneous glutamatergic release and network synchronization typical of early circuits.
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Today, we announced that open-label extension data from Harmony Biosciences’ ongoing Phase 3 trial investigating a potential treatment of Dravet syndrome is being presented at the American Epilepsy Society Annual Meeting in Atlanta today. The data shows clinical meaningful reductions in seizure activity in participants with #Dravet syndrome along with a favorable safety profile. Learn more: bit.ly/48ZaNUQ
#AES2025
#EpilepsyAwareness
#ClinicalTrials
#RareDisease
#DravetSyndrome
#Innovation
#EmpathyAndInnovation

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The gavel has been passed! Many thanks to Dr. Howard Goodkin for a year of exemplary service and congratulations to Dr. Jack Parent, our incoming AES President for 2026! #AES2025


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Our Harmony Biosciences team is excited to be at the 2025 American Epilepsy Society (AES) Annual Meeting in Atlanta! We are looking forward to joining the #epilepsy community and connecting with leaders across healthcare, research, and advocacy. Come say “hello” if you’re there!
#AES2025
#EpilepsyAwareness
#ClinicalTrials
#RareDisease
#DravetSyndrome
#Innovation
#EmpathyAndInnovation

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Earlier today, we announced that we will present new open label extension data from Harmony Biosciences’ rare #epilepsy pipeline at the 2025 American Epilepsy Society (AES) Annual Meeting. Poster presentations will highlight data in an ongoing Phase 3 clinical study for the treatment of #Dravet syndrome. Learn more: bit.ly/3MhQ85u
#AES2025
#EpilepsyAwareness
#ClinicalTrials
#RareDisease
#DravetSyndrome
#Innovation
#EmpathyAndInnovation

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Novo Nordisk's semaglutide fails to slow Alzheimer's progression statnews.com/2025/11/24/nov…
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Scientists have successfully stopped a pig kidney from being rejected by its human recipient.
go.nature.com/47UIdlH
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Getting ready for #Sfn2025 in San Diego🏖️ If you are interested in what the @BarabanLab has been up to lately stop by poster presentations from @joseanemarafiga (MGE) & @PWhyte_Fagundes (zebrafish) | @curestxbp1 @AmEpilepsySoc @hunt_lab @NeurosurgUCSF

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