Johan Henriksson

We can now infer #chromatin #condensation at the #singlecell level! Applied this to new #Bcell #multiome atlas, found out how #AID can avoid #cancer during #somatichypermutation biorxiv.org/content/10.110…

Here are my 12 guidelines for data exploration and analysis with the right attitude for discovery: 1. You never really finish analyzing a dataset. You just decide to stop and move on at some point, leaving some things undiscovered. 🧵

Researchers from @umeauniversity, in collaboration with international colleagues, established G-protein coupled receptors and neuropeptide mutant libraries of C. elegans using CRISPR/Cas9-based approaches. A powerful resource for screening, now published in @NatureComms.

Like hacking on new #technology? #interdisciplinary #postdoc position available in developing a new #microfluidics method for high-throughput #singlecell #wholegenomesequencing of #bacteria henlab.org/postdoc-resolv…

Also, we found that #atypical #monocytes are locked in a special #cellcycle stage by CDKN1C; regular #singlecell #RNAseq based cell cycle annotation missed this. #ATACseq is a very useful complement!

#Lymphoma through random #mutagenesis avoided by #condensation, driven putatively by somewhat poorly studied #CDK13

We can now infer #chromatin #condensation at the #singlecell level! Applied this to new #Bcell #multiome atlas, found out how #AID can avoid #cancer during #somatichypermutation biorxiv.org/content/10.110…

#postdoc #CARTcell #CRISPR #screening #singlecell henlab.org/postdoc-in-car…

#machinelearning #postdoc #VAE #singlecell henlab.org/postdoc-in-var…

#machinelearning #postdoc #textanalysis #semanticanalysis #VAE henlab.org/postdoc-in-sem…

Seeking #postdocjobs - we want you! The IceLab #multidisciplinary postdoctoral fellowships are accepting applications now. You should have math & #computational modeling skills & a deep interest in working with empirical researchers. Welcome to IceLab! icelab.se/opportunities/…

@strategiskaSSF Swedish funders has to create options to hire prospect PhD students from UA. It would be an absolute win-win deal for this goldmine of talent

We wish to recruit a #phd or #postdoc for #bioinformatics methods development, #singlecell and #crispr on #CAR #Tcell. #python, #bayesianstatistics, #ml helpful! henlab.org

DAF regulates B cell selection in the GC! frontiersin.org/articles/10.33…

Congrats to our first 4 students passing their project course, #modelling #transcriptionfactors & #RBPs using #Tcell #RNAseq data!

Don't forget the most important thing of them all: color figures!

T cell metabolism: new insights in systemic lupus erythematosus pathogenesis and therapy nature.com/articles/s4158…

CyTOF against 110 metabolite transporters and enzymes in immune cells

Wetlab #postdoc position in #Tcell #systemsbiology available @NordicEMBL. Come help us reinvent #immunology! bit.ly/2TnDPHz | @humanimmunenews @ImmunologyNews @CdnImmunol @britsocimm @Immunopaedia @ASImmunology @sangerinstitute @embl @maxplanckphdnet

Our latest work on transcription factors showing mechanistic insights into how they cooperate and its functional impact - great collaboration with Janosch Hennig's group at @embl who experimentally validated our predictions. Thanks Jussi Taipale for generating this great dataset!