固定されたツイート
We are very excited today to share our work in @Nature defining the mechanism of human RAD52 mediated single-stranded DNA annealing in cooperation with replication protein A (RPA) nature.com/articles/s4158…. Thread ⬇️⬇️⬇️ (1/8)
English
The West Lab
50 posts
The West Lab
@SCWestLab
The West Lab @TheCrick studies mechanisms of DNA Recombination and Repair. Tweets by lab members, unless signed SCW. Views are own
London 参加日 Aralık 2022
253 フォロー中721 フォロワー
The West Lab がリツイート
Our article "MCM double hexamer loading visualized with human proteins" published in Nature today! ❄️🔬🧬🎉🥳
Great collaboration with John Diffley's lab. Congratulations to Florian Weissmann, Julia Greiwe and all other authors! rdcu.be/d1F7m
English
The West Lab がリツイート
We are pleased to inform you that the meeting “From Genome Instability to Cancer: A tribute to Angelos Constantinou” that will take place in Carry-Le-Rouet from March 10th to March 13th 2025 is now open for registration on the link: tribute2angelos.fr/page/home/
English
The West Lab がリツイート
📣#RECOMBINATION25 PROGRAMME NOW LIVE!
Exciting news! The first draft of the programme for the 2nd Recombination Mechanisms conference is now available. 🌟
🗓Important Deadlines:
Early Bird & Talk Submission – 28 Nov 2024
Poster Submission & Registration Deadline – 13 Mar 2025
Don’t miss out—check out the programme and get all the details here:
bit.ly/4ekGnMz
English
@Jiangchuan_Shen While we observed interaction between the N-terminus of RPA (DBD-F, DBD-A and DBD-B) with RAD52, it is dispensable for the stimulation we observed in the single-stranded DNA annealing assay (Extended Data 11g).
English
@SCWestLab @Nature What is the function of N-terminus of RPA here considering the Rad52/RPA interaction?
English
We are very excited today to share our work in @Nature defining the mechanism of human RAD52 mediated single-stranded DNA annealing in cooperation with replication protein A (RPA) nature.com/articles/s4158…. Thread ⬇️⬇️⬇️ (1/8)
English
The West Lab がリツイート
Delighted to share that my manuscript of "Mechanism of single-stranded DNA annealing by RAD52-RPA complex" is now in Nature!
The West Lab@SCWestLab
We are very excited today to share our work in @Nature defining the mechanism of human RAD52 mediated single-stranded DNA annealing in cooperation with replication protein A (RPA) nature.com/articles/s4158…. Thread ⬇️⬇️⬇️ (1/8)
English
This work was an incredibly collaborative effort between our group (@LukeGreenhough, @ilirjanabajrami @Tuppi1987), the fantastic facilities at the @TheCrick, and funded by @BBSRC and @ERC_Research
English
Our structural, biochemical and biophysical analyses provide a model by which human RAD52 open-ring cooperates with RPA to facilitate single-stranded DNA annealing repair. Our findings may provide new ways of targeting RAD52 in BRCA2 deficient tumours (7/8)
English
Looking forward to it!
Fusion Conferences@Fusion_Conf
@SCWestLab we're looking forward to your presentation at #DNARepair24 in Malta this October! 🇲🇹 Please RT to let your followers know you'll be speaking & that Early Bird & Talk Submission close on 02 May 2024. Find out more ➡️bit.ly/talksub_DNARep…
English
📣@TheCrick has launched The Translation Scholar 🎓 initiative, a new role that combines #AcademicResearch with #Entrepreneurship to bring technologies to market. Congrats to @lola_anaid for being the inaugural holder.🔬💼 We're also hiring! lnkd.in/dV-T2rxm
English
The West Lab がリツイート
Congratulations to Caroline Hill and Xiaodong Zhang on being awarded almost £6 million in @wellcometrust Wellcome Discovery Awards to study DNA repair and organ development in zebrafish and humans 🥳
crick.ac.uk/news-and-repor…
English
Our latest paper uses structural biology, biochemistry & biophysics to reveal the two-step catalytic mechanism of the human nucleotide pool sanitiser DNPH1. This will aid the development of novel inhibitors, which may be of use in breast cancer treatment. nature.com/articles/s4146…
English
The West Lab がリツイート
We awarded our annual Translation Prize last night, recognising researchers at the Crick who are applying their research in a real-world setting.
Congratulations to our winner Anaid Benitez, runner-up Andreia Bernardo and all the nominees! 🏆🎉crick.ac.uk/news/2023-10-1…
English