The West Lab

50 posts

The West Lab banner
The West Lab

The West Lab

@SCWestLab

The West Lab @TheCrick studies mechanisms of DNA Recombination and Repair. Tweets by lab members, unless signed SCW. Views are own

London Katılım Aralık 2022
253 Takip Edilen721 Takipçiler
Sabitlenmiş Tweet
The West Lab
The West Lab@SCWestLab·
We are very excited today to share our work in @Nature defining the mechanism of human RAD52 mediated single-stranded DNA annealing in cooperation with replication protein A (RPA) nature.com/articles/s4158…. Thread ⬇️⬇️⬇️ (1/8)
English
4
58
204
32.6K
The West Lab retweetledi
Costa Lab
Costa Lab@CostaLabCrick·
Our article "MCM double hexamer loading visualized with human proteins" published in Nature today! ❄️🔬🧬🎉🥳 Great collaboration with John Diffley's lab. Congratulations to Florian Weissmann, Julia Greiwe and all other authors! rdcu.be/d1F7m
Costa Lab tweet media
English
6
28
127
9K
The West Lab retweetledi
ConstantinouLab
ConstantinouLab@ConstantinouL·
We are pleased to inform you that the meeting “From Genome Instability to Cancer: A tribute to Angelos Constantinou” that will take place in Carry-Le-Rouet from March 10th to March 13th 2025 is now open for registration on the link: tribute2angelos.fr/page/home/
ConstantinouLab tweet media
English
2
30
48
5.3K
The West Lab retweetledi
Fusion Conferences
Fusion Conferences@Fusion_Conf·
📣#RECOMBINATION25 PROGRAMME NOW LIVE! Exciting news! The first draft of the programme for the 2nd Recombination Mechanisms conference is now available. 🌟 🗓Important Deadlines: Early Bird & Talk Submission – 28 Nov 2024 Poster Submission & Registration Deadline – 13 Mar 2025 Don’t miss out—check out the programme and get all the details here: bit.ly/4ekGnMz
Fusion Conferences tweet media
English
1
6
4
1.6K
The West Lab
The West Lab@SCWestLab·
@Jiangchuan_Shen While we observed interaction between the N-terminus of RPA (DBD-F, DBD-A and DBD-B) with RAD52, it is dispensable for the stimulation we observed in the single-stranded DNA annealing assay (Extended Data 11g).
English
0
0
0
122
The West Lab
The West Lab@SCWestLab·
We are very excited today to share our work in @Nature defining the mechanism of human RAD52 mediated single-stranded DNA annealing in cooperation with replication protein A (RPA) nature.com/articles/s4158…. Thread ⬇️⬇️⬇️ (1/8)
English
4
58
204
32.6K
The West Lab
The West Lab@SCWestLab·
Our structural, biochemical and biophysical analyses provide a model by which human RAD52 open-ring cooperates with RPA to facilitate single-stranded DNA annealing repair. Our findings may provide new ways of targeting RAD52 in BRCA2 deficient tumours (7/8)
The West Lab tweet media
English
2
0
9
714
The West Lab
The West Lab@SCWestLab·
Merry Christmas from the West lab 🎄
The West Lab tweet media
English
1
3
41
3.7K
The West Lab
The West Lab@SCWestLab·
Our latest paper uses structural biology, biochemistry & biophysics to reveal the two-step catalytic mechanism of the human nucleotide pool sanitiser DNPH1. This will aid the development of novel inhibitors, which may be of use in breast cancer treatment. nature.com/articles/s4146…
The West Lab tweet media
English
1
14
57
7.9K
The West Lab retweetledi
The Francis Crick Institute
The Francis Crick Institute@TheCrick·
We awarded our annual Translation Prize last night, recognising researchers at the Crick who are applying their research in a real-world setting. Congratulations to our winner Anaid Benitez, runner-up Andreia Bernardo and all the nominees! 🏆🎉crick.ac.uk/news/2023-10-1…
English
0
2
14
4.6K

Keşfet

@Jiangchuan_Shen @Nature @LukeGreenhough @ilirjanabajrami @Tuppi1987 @TheCrick @BBSRC @ERC_Research