Benedict Chambers
1.1K posts
Benedict Chambers
@Agingfencer
Former president of @FIEathletecom, ex fencer for @fencingireland Chairman of @difcricket, NK cell and dendritic cell biologist @KarolinskaInst
가입일 Ekim 2015
149 팔로잉375 팔로워
Benedict Chambers 리트윗함
New work from our group and Kim Thrane's resolving the immune phenotype of sinonasal cancer with TCR/BCR profiling in tissue sections. SNC are sky-high for Treg cells and Treg clones colocalise with CD8 T and B cells in CXCL9+ niches. #spatialVDJ #scRNASeq
biorxiv.org/content/10.648…
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And this why boys and girls you need to know the reagents that you are using
Sholto David@addictedtoigno1
Today I'm posting a new blog about an astonishing scientific own goal. Hundreds of papers have reported using a completely wrong antibody to investigate the tumor suppressor p16. This mistake has happened because scientists have muddled the names of two proteins 🧵
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Benedict Chambers 리트윗함
So we blocked IFNγ in Mtb infected macaques and….the animals were fine. Turns out mice overestimate the importance of IFNγ in TB because IFNγ drives iNOS in mice but not macaques or humans. This means we don’t actually know how T cells suppress Mtb. rdcu.be/ff9GB
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@Agingfencer @lpachter that's a different endpoint, which might not match the biological question asked.
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This is false.
RT-PCR of a gene-of-interest is an independent replicate. Even if the replicate is less accurate, it's still of value, since in many studies (e.g. scRNA-seq) there are no replicates at all (!)
Of course ideally one designs good experiments from the outset.
Oded Rechavi@OdedRechavi
There's no reason to confirm RNA-seq results with RT-PCR
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@klaasm67 He obviously tipped off the press because there were cameras on both sides of the river
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Unique footage of Julius Caesar crossing the Rubicon with his legions (colorized). On this day in 49 BC. It precipitated the Roman Civil War, which ultimately led to Caesar becoming dictator and the rise of the imperial era of Rome.
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Opening of @ASP_GPO @AmgenFoundation first day at @Cambridge_Uni for the European symposium 2025….the Karolinska cohort will present their findings today
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ANOTHER F2 WIN AND THE CHAMPIONSHIP LEAD FOR ALEX DUNNE! ☘️
It might be the Irishman’s best win yet, through heavy rain at the legendary Spa circuit in Belgium 🇧🇪
Yet again, there was an Offaly jersey in the pitlane as Dunne celebrated with his crew after a memorable win
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Benedict Chambers 리트윗함
The MDV Lab is hiring! We have a Research Assistant position (part time) to characterize EBV virus-specific T cells in people with multiple sclerosis, funded by the @mssocietyuk.
imperial.ac.uk/jobs/search-jo…
Come work with us!
Please feel free to share.
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Starting the week strong with this powerful #macrophage full of phagosomes! 💪 #MicroscopyMonday #electronmicroscopy #bioart
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@KingOfPathogens Am I missing something? Why is the German band Toxoplasma not in there?
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For those immunologists still on twitter - from the marrow to the thymus, from innate to adaptive - will consider suggestions - but need help for the B cells open.spotify.com/playlist/0aCA8…
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@OlympicStatman To be fair I follow you on Twitter and not Tom Jones...so there is that
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My great-grandad and Tom's father worked in the same colliery. Can't help thinking he worked much better for himself than me...
Tom Jones@RealSirTomJones
60 years ago I released It’s Not Unusual, and what a ride it’s been! Back then I would never have believed this one tune would have led on to such a wonderful life and career, full of music, fantastic people and touring all over the world. None of this would have been possible…
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Benedict Chambers 리트윗함
There are now >550 inborn errors of immunity 🧬. Latest update from IUIS IEI c’tee is now available on IUIS website & will be formally published soon. Great to be part of this team providing an important resource for all. Well done @IsabelleMeyts @cecipolih & all ctee members!
International Union of Immunological Societies@iuis_online
The 2024 IUIS Inborn Errors of Immunity (IEI) Classification has arrived! Explore our latest insights now at iuis.org/committees/iei. Find the report under “Annual 2024 Report”!
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Benedict Chambers 리트윗함
For the first time in 5 years Covid is relatively quiet during the holiday season. The XEC variant marches on (latest CDC genomic surveillance below) slowly advancing as % of attributable cases. Fortunately, it's not one that poses a big challenge to our now conditioned immune response
#variant-proportions" target="_blank" rel="nofollow noopener">covid.cdc.gov/covid-data-tra…
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While it is officially ‘too hot’ in Canberra, it is nevertheless important to remind those that might be inclined:
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