Jon Brown Lab

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Jon Brown Lab

Jon Brown Lab

@JonBrownLab

Twitter for the Jon Brown Lab, located in the division of cardiovascular medicine at Vanderbilt University Medical Center. @VUMChealth 🧬 ⚓️

Nashville, TN 가입일 Nisan 2020
244 팔로잉131 팔로워
Jon Brown Lab 리트윗함
Javid Moslehi
Javid Moslehi@CardioOncology·
Big congrats to outstanding colleague & "Cardio-Immunologist" extraordinaire! & fellow PRB3 "neighbor" (well...until a few months ago)! @VUMChealth @VUMC_heart @AmandaDoranLab @JonathanBrownMD @JonBrownLab @JaneFreedmanMD @CircRes @AHA_Research @annetkiraboc1 @nhpetunia
Circulation Research@CircRes

Join us in welcoming our new #TechnicalEditor @CircRes Dr. Amanda Doran MD PhD from the Division of Cardiology @VUMC_heart. Her research focuses on the role of innate immunity and #inflammation resolution in #atherosclerosis. Congratulations! @AmandaDoranLab

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Jon Brown Lab 리트윗함
Nature Portfolio
Nature Portfolio@NaturePortfolio·
The findings of a study in Nature demonstrate the potential of in vivo base editing as a possible treatment for Hutchinson–Gilford progeria syndrome and other genetic diseases by directly correcting their root cause. go.nature.com/38ktlQ1
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Nature Portfolio
Nature Portfolio@NaturePortfolio·
News & Views: No cure exists for the lethal premature-ageing condition Hutchinson–Gilford progeria. A gene-editing tool offers a way to treat the condition in mice, according to a Nature paper. Could this approach lead to an effective therapy? go.nature.com/3oom0EJ
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Jon Brown Lab 리트윗함
Javid Moslehi
Javid Moslehi@CardioOncology·
Congratulations to @SarnoffCardio & @BrighamFellows alumnus/current @VUMChealth cardiologist Dr. John Brown. Really nice story & demonstrating power of teamwork. Can studying progeria provide insights into CV aging? @JonBrownLabVUMC @saptarsi_haldar @tmmichelangelo @Progeria
Jonathan Brown@JonathanBrownMD

So proud of this work demonstrating DNA base editing treatment for #progeria in human cells & mouse model. Amazing collaborative team @davidrliu @NIHDirector @LukeKoblan & Mike Erdos at NIH and my @VUMCResearch team @lindsaymdavison & Sean Doherty rdcu.be/cc90j

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Jon Brown Lab 리트윗함
Jon Brown Lab 리트윗함
David R. Liu
David R. Liu@davidrliu·
Today we report the use of base editing in patient-derived cells and in mice to correct the most common cause of progeria, the devastating rapid aging disease. Progeria is typically caused by a dominant negative C•G-to-T•A point mutation in LMNA. 1/11 drive.google.com/file/d/1oH4W0z…
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