Kaila Lab

Our new study in collaboration with Wolfgang Löscher lab about the NKCC1 role in epilepsy: "Deletion of the Na-K-2Cl cotransporter NKCC1 results in a more severe epileptic phenotype in the intrahippocampal kainate mouse model of temporal lobe epilepsy."

Accepted paper online! The story of the surprising results of a negative control becoming an entire new project! insight.jci.org/articles/view/…

Still 5 days left to submit an abstract to the FENS virtual Forum. A great opportunity to share your neuroscience online in July.

Congratulations to Martina Mavrovic with the excellent defense of her doctoral thesis done in our lab (@KailaLab5)! Our huge thanks to the official opponent Jean Christophe Poncer (@PoncerLab) for a super interesting discussion of the KCC2 role in the perinatal rodent cortex!

The result of our fruitful collaboration with Dan McCloskey lab @neurolab has just been published in @CurrentBiology : Nest Carbon Dioxide Masks GABA-Dependent Seizure Susceptibility in the Naked Mole-Rat cell.com/current-biolog…

Our recent story is here: Loss of non‐canonical KCC2 functions promotes developmental apoptosis of cortical projection neurons link -> embopress.org/doi/10.15252/e… By @MartinaMavrovic, @Kvarovpauk , Eric Delpire, Laszlo Vutskits, Kai Kaila, and Martin Puskarjov.

Endogenous responses in brain pH and PO2 in a rodent model of birth asphyxia biorxiv.org/content/10.110…

Amazing annual Brain & Mind symposium #brainmind19! Thanks to the student council for organizing it and inviting so many great speakers. If you missed the poster session, here's the poster that represented the lab this year by our PhD student Alexey Pospelov

Our PhD student Inkeri Spoljaric successfully defended her PhD thesis today! Congratulations Inkeri!!

@helsinkiuni @inmed_u1249 Time: Thursday, May 16 at 11:00-12:00. Place: Biocenter 2, auditorium 1041 (Viikinkaari 5)

Join us at the #Neuroscience seminar by Roustem Khazipov on May 16th at the Biocenter 2, @helsinkiuni Topic: Early activity patterns in the developing brain. Khazipov lab at @inmed_u1249 -> inmed.fr/en/en-activite… #neonatal #cortex #hippocampus #sharpwaves

Our PhD student Inkeri Spoljaric is defending her thesis titled: “GABAergic Signaling and Neuronal Chloride Regulation in the Control of Network Events in the Immature Hippocampus" on May 17th at 12:00 in Infocenter Korona. link to the thesis - helda.helsinki.fi/handle/10138/3…

#lapsiköyhyys hs.fi/sunnuntai/art-…

A #new antibody search engine with publication data. #Free online platform for academic scientists! landing.benchsci.com/academic?utm_c… #phdchat #openaccess #openscience

Our recent story is here: KCC2-Mediated Cl− Extrusion Modulates Spontaneous Hippocampal Network Events in Perinatal Rats and Mice cell.com/cell-reports/f…

Our team is here: helsinki.fi/en/researchgro…