Luke Harrison

@pmoyniha @_Matt_Hannah @vikasnavaratna Based on some recent work that @mbehr_mcgill, Vivek Kapur and I published (microbiologyresearch.org/content/journa…), we have a hierarchical genome alignment that can be used for orthology (some caveats including only some genomes). Feel free to reach out if I can help!

@_Matt_Hannah @vikasnavaratna This is an M.tuberculosis H37Rv to M. bovis BCG comparison. Much of the genome is close to 99% identical, with a few deletions.

Is there anyone out there that can point me towards a simple way to take a list of genes (over 1000) from organism A and list the orthologs in organism B?

@pmoyniha @_Matt_Hannah @vikasnavaratna Hi, I have found that the high degree of identity within the MTBC sometimes confuses automated orthology software based on reciprocal best hits.