Matt Segar

Medicine lost one of its greats this week. My grandpa, Dr. William (Bill) Segar, had an illustrious career that spanned nearly 60 years from @IUMedSchool and @RileyChildrens, @YaleMed, @MayoClinicCV, and @uwsmph and @WiscPediatrics.

Been an exciting journey! Even more excited for what’s next.

We’ve been acquired!

Can standard ECGs flag aortic stenosis years earlier and predict higher mortality post-TAVR? Yes. 🫀 @CardioCareToday highlighted groundbreaking research by Dr. @MattSegar (@Texas_Heart). At AccurKardia, our investigational AK-AVS pipeline is turning the standard ECG into a powerful, predictive biomarker for structural heart disease. Check the interview: cardiocaretoday.com/post/ai-enhanc… #AorticStenosis #TAVR #HealthTech #Cardiology #MedTech #AI #BetterOutcomes

@alexandra_regia @DrRoderickTung @HRSonline This is such a good topic. Congrats!

Thrilled to share that I’ve been selected to pitch at the AFib Shark Tank at #HRS2026. As a longtime fan of the format, it’s exciting to now be part of it. Grateful to @DrRoderickTung for inspiring me to think outside the box about AF mechanisms and mapping strategies that may lead to new treatment approaches. More to come!

#WAFIB2026 ⁦@westernAFib⁩ ⁦@nmarrouche⁩ ⁦@SanaAlkhatib9⁩ ⁦@PassmanRod⁩ ⁦@Phiso_de⁩ ⁦@TinaBaykaner⁩ ⁦@MattSegar⁩

On the standards of reporting of P-wave abnormalities in electrocardiographic studies heartrhythmjournal.com/article/S1547-…

Electrocardiographic P-wave Parameters and Lifetime Atrial Fibrillation Risk: A Multi-Cohort Study @MattSegar heartrhythmjournal.com/article/S1547-…

New peer-reviewed evidence for AI-ECG in aortic stenosis. Big thanks to Dr. @MattSegar and the Texas Heart Institute team for leading this work. academic.oup.com/ehjdh/advance-… AK-AVS is investigational and not FDA-cleared.

@balrik @ImperialEP Seems similar to this onlinelibrary.wiley.com/doi/abs/10.111…

#EPeeps 1. Have you seen slow pathway activation during AVNRT? Using Ripple we @ImperialEP can. 2. The His seen during AVNRT may not be His at all... See our manuscript below! #openaccess heartrhythmjournal.com/article/S1547-…

@jamespotter Great product. Is battery life optimization on the roadmap? Seems to use more battery life than I anticipated.

WhyFi 1.1.0 shipped! ⭐️ New leaderboard at whyfi.network/leaderboard/ (brag about how fast your wi-fi is, easily unseat me from my current #1 spot) 🤖 New menu option Copy Stats for AI Help to paste your metrics to your LLM of choice and diagnose issues ℹ️ Better (and easier to understand) tips to fix issues with your wi-fi Go to Options > Check for Updates or quit the app and re-download manually at whyfi.network/download/

Development and Validation of a Novel Machine Learning-Based Algorithm to Predict Incident Atrial Fibrillation – A Multicohort Analysis heartrhythmjournal.com/article/S1547-…

@shaan_khurshid @MGHHeartHealth @MGBResearchNews @broadinstitute @broad_ml4h Did you look at decision curves by chance?

Honored to present our work using ECG-AI to predict adjudicated cardiac arrest as featured science #AHA25 @MGHHeartHealth @MGBResearchNews @broadinstitute @broad_ml4h

POLY-HF trial: Polypill containing metoprolol, spironolactone, and empagliflozin improved EF, QoL, and adherence, and reduced HF hospitalizations at 6 months in HFrEF patients compared to usual care. #AHA25 View the slides here: clinicaltrialresults.org/wp-content/upl…

Never doubted ourselves.

@SpineNeuro @SenBillCassidy I don’t think it’s a controversial take at all

Controversial opinion: the AMA is a coding business masquerading as a physician organization help.senate.gov/rep/newsroom/p…

@DrBasedMD @olsonplanner Exactly

@olsonplanner Oh good, another reminder of how f'd the current generation of docs are. 15k/mo into sp500 would've gotten him to 8m. Nothing special to see here at all.

17 years ago, I started working with a young orthopedic surgeon fresh out of training. He was making $60k as a resident. Then $600k as an attending. Today, he’s 51 with $10 million in assets. Here’s exactly how we did it 👇

@thisisalimirza @DrDiGiorgio Things like recodemedical.com can help

@DrDiGiorgio How do doctors usually learn this?

American doctors aren’t rewarded primarily for being good doctors. They’re rewarded for mastering the billing labyrinth. The physician who can recite NCCI edits, apply the right modifier, and know which codes are bundled (or can be unbundled) is the one who thrives.

Interesting case with PMCardio - Queen of Hearts. On call today and paged to ED for chest pain. ECG looked completely “benign”. Clinical story suggested an ACS event. We decided to take him to the Cath lab anyways, but used the app to see if I missed anything. QoH noted a STEMI equivalent. Patient ended up having a LCx occlusion. Ended up buying a subscription to the app for that alone. @PowerfulMedical @MartinHerman_ @RobertHermanMD

I experienced my first AI scribe hallucination today. What I said: "Heart rate 71 bpm" What the AI documented: "Electrocardiogram: Normal sinus rhythm" No ECG was performed. The AI scribe extrapolated from basic vital sign data and generated documentation for a procedure that never occurred. Remember, AI scribes are powerful tools, but they're not infallible. They can (and will) "hallucinate" by creating plausible-sounding but completely fictional content. We cannot delegate our professional responsibility to validate documentation. The technology is impressive, but physician oversight remains non-negotiable. Has anyone else experienced this?

AccurKardia launches clinical pilot for AK+ Guard. Three arm study, 150+ patients across care settings. AI hyperkalemia risk from Lead I ECGs, works with FDA cleared wearables. Details: businesswire.com/news/home/2025… (Investigational, not FDA cleared.)