Center for Precision Neuroimaging

Dr. Rahul Desikan & his team at UCSF @PrecisionNeuro are building a free online genetic platform for #ALS patients to calculate genetic risk. bit.ly/2C3tbMl

Polygenic hazard score, amyloid deposition and Alzheimer's neurodegeneration. Beyond APOE, polygenic hazard scores in living subjects were associated with amyloid deposition and neurodegeneration in susceptible brain regions. bit.ly/2Nex6dG @rahuldesikan @ADNI3study

'Polygenic hazard score, amyloid deposition and Alzheimer's neurodegeneration' --> New #research from the @PrecisionNeuro team. bit.ly/2BcPj6G

"...these findings further suggest a nuanced relationship between polygenic risk and markers of amyloid deposition, pathological tau and neurodegeneration"

This is my own genetic data run on our tools - looks like I'd benefit from stem cells and oxidative therapies - this is the real potential for #Genomics for #ALS #treatments - we can do this and any #PALS #fightALS

'Partitioning the genetic architecture of #ALS.' New results from @PrecisionNeuro via @biorxivpreprint --> bit.ly/2GRDGXX

new work from my laboratory

Our new findings suggest that subsets of ALS patients are at elevated genetic risk for FTD, cardiovascular, or immune dysfunction. Developing multiple pathway polygenic scores in this regard would be important for informing therapies.

Ten observations about ALS! Which of these were unknown to you? #ALS

Welcome to the official page of the Laboratory for Precision Neuroimaging @UCSF! Led by Drs. Rahul Desikan @rahuldesikan and Leo Sugrue @LeoSugrue. Please follow us for major updates and news from the lab!

GWAS for dummies