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I have moved over to BlueSky. you can find me there:
@mtrost.bsky.social
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Matthias Trost ๐ช๐บ
5.4K posts
Matthias Trost ๐ช๐บ
@TrostLab
Professor of Proteomics. Views are my own. Retweet โ endorsement @[email protected] @mtrost.bsky.social
Newcastle upon Tyne, England ๊ฐ์
์ผ Temmuz 2013
2.1K ํ๋ก์3.3K ํ๋ก์
Competitive Postdoctoral Fellowships - Marie Skลodowska-Curie Actions (europa.eu) are now available.
If interested to join us - learning proteomics or being a proteomics person and learning more biology, please send an email.
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@lpachter So if one wants to use a dimension reduction, which one would you suggest that people use?
haven't been following that....
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Yes another analysis showing how poor t-SNE and UMAP are. Only 60% of the ten nearest neighbors are even among the 100 nearest neighbors in high dimension.
How many such demonstrations will it take to convince people to abandon these plots?
Jan Lause ๐ฆ @janlause.bsky.social๐ฆ@JanLause
tSNE/UMAP preserve neighbors in a "soft" sense: Yes, tSNE recalls only ~30% of neighbors exactly. But ~60-80% of the 10 nearest tSNE neighbors are among the 100 nearest true neighbors! So even if some tSNE neighbors are not next-door neighbors, most are "from the same block".
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Congratulations to @bmss_official , @PerditaB and everyone involved in making this possible!
A much needed investment into UK's mass spectrometry infrastructure.
Thank you, @The_MRC @UKRI_News !
Medical Research Council@The_MRC
ยฃ49.35m to support the Critical Mass UK (C-MASS) project, co-delivered with @EPSRC, that will develop a UK-wide hub-and-spoke infrastructure to advance our capability in mass spectrometry.
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@Fuechsle_talk Sat last time within the West Ham area and had rather unpleasant experience with the West Ham fans.
I think I will rather stay home and watch it from there.
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Amidst antiZionism is Soviet Propaganda nonsense, and even the accurate Settler+Colonialism logic, we should not lose sight of the fact that Israel would not have come into existence without the active support of Josef Stalin.
This is an interesting read..
scholar.harvard.edu/files/martinkrโฆ
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@VdangioE3lab @OxfordOncology ยฃ34 per hour. yes, things do get more expensive, but your university has more than enough money and seems to offer surprisingly little in return.
just come and join us :-)
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The charges of our microscopy facility @OxfordOncology have been doubled last year (there was no new equipment bought) 70ยฃ/hour. What are your charges ?
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again not working.
don't really know how I am supposed to be working without Pubmed.
Newcastle University IT Service@NU_ITservice
@TrostLab @NCBI @NLM_NIH @StudentsNCL @NCBI @NLM_NIH we have been in contact with NLM Support (case number #CAS-1234575-J7P7W3) as traffic from our network is being rejected; weโve chased for updates but had no response since 15th Dec. Can you provide an update on our case please?
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@JProteomeRes @slavov_n @thalexandrov advertising a special issue 2 weeks before the submission deadline is perhaps a little late?
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๐ฌ Call for Papers: Special Issue on cutting-edge advances in single-cell analysis for a holistic understanding of biological processing involving #metabolites, #proteins, & #nucleicacids. Special Issue managed by @slavov_n & @thalexandrov.
Submit now: go.acs.org/7E1
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totally agree. I always try to hire people that are smarter than me!
Jessica Blair@JessicaMABlair
This is truly dreadful advice. Alternatively, find a supervisor that values your opinions and ideas, and that seeks to elevate and promote you, not steal your ideas to inflate their fragile ego!
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Dear @NCBI @NLM_NIH
in our institution @StudentsNCL in the UK we cannot access Pubmed or any other NIH/NCBI website anymore. this has been intermittently going on for months!
Out IT says it comes from your side.
can you please look into this!
thanks a lot!
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UK has joined Horizon Europe again.
If you are interested in a Marie Curie Fellowship application with our lab in mass spectrometry, phagosome biology/innate immunity or drug discovery, please contact me.
in the past we had 3/3 funded.
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Matthias Trost ๐ช๐บ ๋ฆฌํธ์ํจ
How do #macrophages reprogram following the uptake & digestion of apoptotic cells? Can these macrophages then trigger naรฏve cells?
We employed SILAC and DIA-MS to answer these questions in our latest preprint. @TrostLab @Dr_Andy_Frey
Check it out here:
biorxiv.org/content/10.110โฆ
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@TheBrysonLab Not sure if this is the best paper. This paper was the highlight of the ER/phagosome controversy vlaiming there is no ER on the phagosome.
I think by now the vast majority of people in the field however believe that (at least some) ER proteins are on the phagosome.
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Found what I was looking for: #fig1" target="_blank" rel="nofollow noopener">sciencedirect.com/science/articlโฆ
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OK #phagosome friends, anyone know a paper where a protein was targeted to plasma membrane and then shown to traffic to phagosome upon phagocytosis? (I'm sure one exists!)
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@NIH
we cannot access #PubMed or any other NIH site from our university network at @UniofNewcastle anymore.
our IT staff states this is blocked at your side.
Are you aware of that?
this is all rather frustrating!
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@SkySportsNews
Why are you not showing all Sunday @Bundesliga_EN games?
Not sure why I should pay for that when you are barely showing any games!
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@chrashwood lol.
in the UK there is no capital equipment grant scheme that provides enough money to pay for an Astral with all bits and bops.
I think they may notice that in their sales numbers.
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The lab has just been awarded an 8-year grant to study coronavirus replication! ๐พ๐
Job ads will appear around end October but we are particularly looking for PDRAs with coronavirus reverse genetics experience or CL3 coronavirus-host interactions. ~Mar 2024 start.
North West, England ๐ฌ๐ง English
Matthias Trost ๐ช๐บ ๋ฆฌํธ์ํจ
For any of my #virology or #massspec followers who are contemplating migration to bluer destinations - here is how I got my invite code.
Anne Carpenter, PhD@DrAnneCarpenter
You can join us over there! docs.google.com/forms/d/e/1FAIโฆ
Liverpool, England ๐ฌ๐ง English