Martín Lázaro

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Martín Lázaro

Martín Lázaro

@mlazqui

Medical oncologist. Lung and genitourinary cancer. #lcsm #pcsm #kcsm

Vigo 가입일 Eylül 2010
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David H Aggen, MD PhD
David H Aggen, MD PhD@Dr_Aggen·
UC Takeaways from #ASCOGU26 1) KEYNOTE-B15 is a landmark. Periop EV+pembro vs gem/cis in cis-eligible MIBC: EFS HR 0.53, pCR 55.8% vs 32.5%, OS benefit. First regimen to displace cisplatin in curative-intent bladder cancer in ~25 yrs.
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What REALLY makes a good oncologist? in @JCO_ASCO After 10 years and 203 JCO essays, one thing became clear: expertise alone isn’t enough. Patient-centered care. Clear, authentic communication. Emotional intelligence. And the harder work Showing up again and again. Openness
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ESMO-ESTRO consensus statements on the safety of combining radiotherapy with EGFR, ALK, or BRAF/MEK inhibitors in @ESMO_Open. Evidence-based consensus statements providing guidance on the safety of combining RT with EGFR, ALK, or BRAF/MEK inhibitors. esmoopen.com/article/S2059-…
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IMVIGOR011: ctDNA guided adjuvant atezolizumab in MIBC shows a ctDNA risk adapted approach identified high risk patients who benefit from ICI therapy, sparing persistently ctDNA-ves (at much lower risk) toxicity. Here #GU26 we show ctDNA+ves have dynamic MTM levels (a bit like
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Disitimab Vedotin (HER2/MMAE ADC) was tested in HER2-positive (n=73, RR 55%) and HER2-low (n=78, RR 53%) pretreated advanced bladder cancer outside of China. No clear efficacy difference according to HER status(PFS 6 months and OS 17-20 mnths). Only about 20% of UC patients are
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Toni Choueiri, MD
Toni Choueiri, MD@DrChoueiri·
ASCO GU 2026 – Top 15 Trials with Potential Practice Impact @ASCO #GU26
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OncoAlert
OncoAlert@OncoAlert·
OncoAlert🚨The #AUC3 WEEK 2026 Their Publication is NOW OUTARTICLE HERE: 👉 buff.ly/bAgkPQC Presenter Dr. Brian Rini 🇺🇸 (Adjuvant Therapy Debate) CON in #KidneyCancer RCC Conclusions There are relevant data points on both sides of the benefit:risk equation to consider in the application of adjuvant pembro in individual resected high-risk RCC patients Benefits are real but modest with some missing information about the appropriate treatment of recurrence Life-altering toxicity in patients who may not recur is sobering RAMPART supports the benefit of adjuvant IO, and highlights confinement of the benefit to the highest risk patients We need better prognostication tools and predictive/prognostic biomarkers (?KIM-1) This is about to get more complicated with Pembro/belzu.. @DrRanaMcKay @montypal @DrRosenbergMSK @Wanling50578056 @Dr_Aggen @AlbigesL @apolo_andrea @OncoBellmunt @bergsa83 @bilenma @BraunMDPhD @drjefstathiou @PGrivasMDPhD @shilpaonc @arihakimi @HHammersMD @DrDanielHeng @MichelleDunno17 @EJonasch @koshkin85 @advocatekidneys @UrogerliMD @SurenaMatinMD @maughanonc @BradMcG04 @JoshMeeks @motzermd @AndreaNecchi @SimaPorten @tompowles1 @brian_rini @sonpavde @ChadTangMD @MichvdHeijden @VincentWenxinXu @TiansterZhang @Mustafajsalehmd @mzugman @AUC3_Official #kidneyCancer #BladderCancer
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Dra. María Natalia Gandur Quiroga
Dra. María Natalia Gandur Quiroga@nataliagandur·
FORMULA-509 @EUplatinum 2026 pubmed.ncbi.nlm.nih.gov/41672869/ Can we safely intensify short-course ADT during salvage RT after prostatectomy? @DrPaulNguyen @DrRanaMcKay 345 pts, sRT + 6 mo GnRH agonist ▪️ Bicalutamide ▪️ vs Abiraterone + Prednisone + Apalutamide 🎯 Overall population ▪️ 3-yr PFS: 74.9% vs 68.5% HR 0.71 (p=0.063) ▪️ 3-yr MFS: 90.6% vs 87.2% HR 0.57 (p=0.050) ➡️ Did not meet prespecified statistical significance. 🔎 But here is the signal: In pts with PSA >0.5 ng/mL: ▪️ 3-yr PFS: 67.2% vs 46.8% HR 0.50 (p=0.030) ▪️ 3-yr MFS: 84.3% vs 66.1% HR 0.32 (p=0.014) 📌 Absolute MFS benefit: 18.2% 📌 NNT ≈ 5.5 💡 Interpretation: • Not practice-changing for all • Potentially relevant for biologically higher-risk salvage • Raises the key question: 👉 Is 6 months of intensified AR-axis suppression preferable to longer conventional ADT strategies? Quality of life vs oncologic control, the real tension. @OncoAlert @APCCC_Lugano @Silke_Gillessen @AOmlin @Prof_Nick_James @BertrandTOMBAL @LoebStacy @urotoday @ecancer @MedicalwatchHQ #ProstateCancer #SalvageRadiotherapy #ADT #ARPI #EurUrol #GUoncology
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Última oportunidad para sumarte a #OncoPrecision26 📍 Vigo · 19–20 feb 2026 La #OncologíadePrecisión ya forma parte de la práctica clínica: NGS, IA, nuevas dianas terapéuticas y aplicación real en consulta, de la mano de especialistas de referencia a nivel nacional. ‼️👇 Mañana se cierran INSCRIPCIONES: tacticsmd.net/actividad/viii… @OncoHULA @mlazqui @SOG_Galicia
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Manuel Rodríguez
Manuel Rodríguez@CodigoRojo_INN·
Me hace mucha ilusión compartir que somos finalistas en #INNOVAH2025 🙌 Con Código Rojo queremos transformar la forma en la que los médicos acceden a conocimiento y formación, usando #IA como aliada ¿Nos echas una mano con un ❤️ y un RT? @NovartisSpain @SETH__Oficial @sehh_es
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Martín Lázaro
Martín Lázaro@mlazqui·
Real-world data on avelumab in first-line maintenance therapy for advanced or metastatic urothelial carcinoma: the SOGUG-AVELUMAB RWD study | Clinical and Translational Oncology link.springer.com/article/10.100…
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