AAVpapers

MicroRNA-204-5p Ameliorates Renal Injury via Regulating Keap1/Nrf2 Pathway in Diabetic Kidney Disease dlvr.it/T1CVqb

Lentiviral mediated delivery of CRISPR/Cas9 reduces intraocular pressure in a mouse model of myocilin glaucoma dlvr.it/T1C5L7

Deficiency of Transcription Factor SP1 Contributes to Hypertrophic Cardiomyopathy dlvr.it/T1BhL0

EMID2 is a novel biotherapeutic for aggressive cancers identified by in vivo screening dlvr.it/T1B24Q

Tanshinone IIA alleviates bleomycin-induced pulmonary fibrosis by inhibiting Zbtb16 dlvr.it/T19qZd

FTO-mediated m6A modification of serum amyloid A2 mRNA promotes podocyte injury and inflammation by activating the NF-κB signaling pathway dlvr.it/T19cyr

An Aedes-Anopheles Vaccine Candidate Supplemented with BCG Epitopes Against the Aedes and Anopheles Genera to Overcome Hypersensitivity to Mosquito Bites dlvr.it/T19N9n

Tissue-targeted and localized AAV5-DCN and AAV5-PEDF combination gene therapy abrogates corneal fibrosis and concurrent neovascularization in rabbit eyes in vivo dlvr.it/T192nT

Morphological, molecular, and functional characterization of mouse glutamatergic myenteric neurons dlvr.it/T18dJP

An AAV capsid reprogrammed to bind human Transferrin Receptor mediates brain-wide gene delivery dlvr.it/T17P2w

Spatial genomics of AAVs reveals mechanism of transcriptional crosstalk that enables targeted delivery of large genetic cargo dlvr.it/T17C3d

AAV-Mediated Gene Therapy Restores Hearing in Patients with DFNB9 Deafness dlvr.it/T16zJ7

AAV for Gene Therapy in Ocular Diseases: Progress and Prospects dlvr.it/T15xC4

The intrinsic coagulation pathway plays a dominant role in driving hypercoagulability in ANCA-Associated Vasculitis dlvr.it/T15YgD

Gene therapy with bidridistrogene xeboparvovec for limb-girdle muscular dystrophy type 2E/R4: phase 1/2 trial results dlvr.it/T15FG6

Autophagy dysfunction contributes to NLRP1 inflammasome-linked depressive-like behaviors in mice dlvr.it/T151ly

Cas13b-mediated RNA targeted therapy alleviates genetic dilated cardiomyopathy in mice dlvr.it/T14sK9

Regnase-1 overexpression as a therapeutic approach of Marfan syndrome dlvr.it/T14hfP

Fibulin 1, targeted by microRNA-24-3p, promotes cell proliferation and migration in vascular smooth muscle cells, contributing to the development of atherosclerosis in APOE-/- mice dlvr.it/T14VPH

The upregulation of Annexin A2 by TLR4 pathway facilitates lipid accumulation and liver injury via blocking AMPK/mTOR-mediated autophagy flux during the development of non-alcoholic fatty liver disease dlvr.it/T14Fmp