Dr Adjanie Patabendige

Thanks for the invitation @BenedictNeuro An excellent line up of talks. Lots of potential for exciting work in the future!

Well done to all @EHU_Research PGRs that presented at the inaugural PGR Palooza today, including our very own @Brain_Barriers PhD students 👏 @BiologyEHU @edgehill_HRI @ehucardioresprc

Fabulous start to @acmedsci #SUSTAIN10 Leadership programme for women in research 👩‍🔬👏 Looking forward to working with this group of amazing research leaders and the Academy fellows over the next year. @edgehill @edgehill_HRI @LiverpoolCCS

Happy #InternationalWomensDay from @Brain_Barriers 🧠 👩‍🔬 #WomenInScience @BiologyEHU @LiverpoolCCS Also congrats to 6th form student from Belvedere Academy Liverpool for her successful work placement in our lab 👩‍🔬🥳 #STEMeducation @edgehill

Thrilled to see our latest review out! @Brain_Barriers @BiologyEHU @LiverpoolCCS Congrats to my PhD student @CeinwynGrace for her 1st ever 1st author review 🎉 We discuss the therapeutic potential of using nanoparticles to deliver drugs across the #BBB in #dementia 🧠

Thank you to my Secret Santa 😍🎅 @biology @edgehill @acmedsci Wishing all my Twitter/X followers and colleagues a very merry Christmas and a happy New Year! 🎉

Patabendige & Tagalakis group joint Christmas lunch 🎄 An amazing group of colleagues, a pleasure to work with everyday. Great to end the year on a high 🍾 🥳 @Brain_Barriers @BiologyEHU

Dr Rajiv Sankaranarayanan discussed 'Transforming Care in Heart Failure Patients using VIRTUAL WARDS' , concluding the @ehucardioresprc seminar series

Thanks for the invitation @ehucardioresprc @EHU_FHSCM Looking forward to the next couple of seminars @DrRajivsankar and A/Prof Pankaj Garg

Many thanks to our keynote speakers Prof Egle Solito @esolitolab and Dr Reinhard Gabathuler for two very exciting and insightful presentations! Lovely to also see so many brilliant ECR presentations. The future of #BBB research is bright! 👏 🧠#13ECRBBB @EHU_Research @BiologyEHU

@Conasaurus1 @edgehill @MontagneLab Amazing talk Conor! Lovely to meet up after so many years. Great to see your career progression and contribution to the field. #13ECRBBB @Brain_Barriers

On way to @edgehill for the Early Career BBB meeting hosted by @APatabendige Its an early start but get to see the lake District as I go! @MontagneLab

Registration and abstract submission will close soon! Awards & prizes to be won, including the David Begley Excellence Award for Young BBB Researchers (sponsored by Pharmidex). Pls RT @LNeuroscience @BRUKresearch @BMVBSoc @EHU_Research

Updated group photo to welcome new members! L-R: @RosieGaske75026 Project Coordinator, new PhD students Camarra Nazha & Umeshi Karunadasa, @APatabendige and 2nd year PhD student @CeinwynGrace Pls follow @Brain_Barriers our new X profile. @LiverpoolCCS @EHU_Research #WomenInSTEM

Just over a week left to apply to join my #BBB lab as a fully-funded PhD student and be part of this friendly department @BiologyEHU @EHU_Research and @LiverpoolCCS family. Tuition fees and a tax-free stipend of £18,622 per annum is on offer. jobs.edgehill.ac.uk/vacancy.aspx?r…

🚨 Dr. Cicognola @clau_cico from @lunduniversity will give a virtual talk titled "Associations of CSF PDGFRβ With Aging, BBB Damage, Neuroinflammation, and AD Pathologic Changes" 🤩🧠 📅 17th Aug 🕐 1pm UK time 🖱️ *Register* here: ukdri.zoom.us/webinar/regist… Please RT! 🙏🏻 @UKDRI

Very sad to hear the news of passing away of Dr David Begley, one of my PhD supervisors with Joan Abbott at BBB group at KCL @KclPhysiology. I was so lucky to have known him and learn from him. A genuine expert in BBB drug transport. Truly irreplaceable. RIP David 🙏

A mind-blowing paper has come out today in @Nature In 2016, JC Venter Institute scientists trimmed a bacterial genome to its barest minimum required for life to synthesize what they called a "minimal genome" (science.org/doi/10.1126/sc…). Today, a group of scientists from Indiana University reports how that minimal genome evolved over 2000 generations in comparison to the non-minimal genome. The authors found that even when you reduce a bacterial genome to its absolute minimum where every nucleotide matters, the genome undergoes mutational events generation after generation as much as the non-minimal genome. One simply cannot stop the evolution. Just over 300 days of evolution (equivalent to 40,000 years in humans) the minimal cell has gained everything it lacked in fitness on day one in comparison to the non-minimal cell. When comparing the evolved traits between the minimal and non-minimal cells, the scientists found something striking. The evolutionary process increased the cell size of non-minimal cells but not that of the minimal cell. But that is not the striking part. The scientists were able to identify the key mutation that resulted in cell size evolution. And it turned out that the mutation that helped the non-minimal cells to grow bigger is the same that helped the minimal cells to stay smaller. Growing bigger had a survival advantage for non-minimal cells and not growing bigger had a survival advantage for minimal cells. So, the mutation had a context-dependent effect. This just demonstrates that the evolutionary effects on traits have no absolute direction. All that matter is what is beneficial for the organism's survival. The conclusion of the paper is metaphorically a quote from the Jurassic Park movie: “Listen, if there’s one thing the history of evolution has taught us is that life will not be contained. Life breaks free. It expands to new territories, and it crashes through barriers painfully, maybe even dangerously, but . . . life finds a way". (scienmag.com/artificial-cel…) nature.com/articles/s4158…

I'm looking for a research project co-ordinator to join my lab for 18 months. You'll be skilled in cell culture and have some experience as a research assistant or co-ordinator. @EHU_Research Apply via jobs.edgehill.ac.uk/Vacancy.aspx?r…

A fantastic day at the @acmedsci meeting my fellow #AMSspringboard awardees and the wonderful staff! Thank you for the excellent networking opportunity and interactive sessions on Research Leadership 👌👩‍🔬 @AMS_Careers

@AxL_Montagne @GuLabNeuro @ralfhadams @ISD_Research Sad to miss it this time around! One of my favourite BBB meetings...

Great #CVB2023 vascular session yesterday with the brilliant Chenghua Gu @GuLabNeuro, Ralf Adams @ralfhadams, and Martin Dichgans @ISD_Research 🤩