IOVS Journal

New Editorial by IOVS editors Subhabrata Chakrabarti, Anthony Khawaja, Jeremy A. Guggenheim & Janey L. Wiggs updates the journal's guidelines bit.ly/4wpr4eE for ophthalmic genetic studies. doi.org/10.1167/iovs.6…

Machelle Pardue et al. report that L-DOPA Promotes Post-Treatment Neurovascular and Synaptic Homeostasis in Early Diabetic Retinopathy, iovs.arvojournals.org/article.aspx?a….

Bruce Berkowitz et al. share their work on Macular Metabolism in Young and Older Adults: A Preliminary Optical Coherence Tomography Biomarker Study, iovs.arvojournals.org/article.aspx?a….

The ARVO Imaging in the Eye meeting abstracts are now published! iovs.arvojournals.org/issues.aspx?is…

Debarshi Mustafi et al. from the University of Washington use integrative genomic mapping and visualization from curated public datasets to reveal germline RB1 variant diversity in retinoblastoma. doi.org/10.1167/iovs.6…

Colleen M. McDowell et al. from the University of Wisconsin-Madison describe a novel role for CGRP in aqueous humor outflow. doi.org/10.1167/iovs.6…

Xiao-rong Wu, Xianjun Zeng et al. from The First Affiliated Hospital investigate abnormalities in hemispheric lateralization and interhemispheric cooperation in patients with high myopia. doi.org/10.1167/iovs.6…

Maximilian Hammer from University Eye Clinic Heidelberg find that vitrectomy status alters early intravitreal drug distribution in an ex vivo PET-CT study. doi.org/10.1167/iovs.6…

Yanxian Chen et al. from the The Hong Kong Polytechnic University compare longitudinal changes in three-dimensional (3D) macular morphology between repeated low-level red-light (RLRL) therapy and 0.01% low-dose atropine (LDA) treatment in myopic children. doi.org/10.1167/iovs.6…

William Schierding et al. from the University of Auckland investigate structural and microstructural brain changes in glaucoma using multimodal magnetic resonance imaging across primary, secondary, and higher-order visual brain regions. doi.org/10.1167/iovs.6…

Li Li et al. from the First Affiliated Hospital of Xi'an Jiaotong University investigate the effects of shear stress on corneal epithelial homeostasis and the role of the mechanosensor Piezo1 in this process. doi.org/10.1167/iovs.6…

Alexander Stanley et al. from the University of Michigan find that FLVCR2 regulation of intracellular heme modulates vascular tip/stalk specification during retinal angiogenesis. doi.org/10.1167/iovs.6…

Wei Liu, Mingchang Zhang et al. from Tongji Medical College find that YAP regulates the Nrf2 signaling axis to attenuate oxidative stress and neuroinflammation in retinal ganglion cell degeneration. doi.org/10.1167/iovs.6…

Hong Qi et al. from Peking University investigate Epstein-Barr virus-induced upregulation of GPR183 as a potential upstream mechanism in IgG4-related ophthalmic disease. doi.org/10.1167/iovs.6…

Yongxiang Jiang et al. from the Eye, Ear, Nose and Throat Hospital of Fudan University characterize aqueous humor (AH) proteomic alterations in ADAMTSL4-associated congenital ectopia lentis (CEL) and identify disease-related molecular features. doi.org/10.1167/iovs.6…

Srinivas R. Sadda et al. from Doheny Eye Institute determine the prevalence and imaging characteristics of thin and thick idiopathic epiretinal membranes (ERMs) using high-resolution OCT. doi.org/10.1167/iovs.6…

Jiang Bian et al. from Shandong Key Laboratory of Eye Diseases find that ocular IL-1α/IFN-γ delay the corneal wound healing in rheumatoid arthritis through mitochondrial dysfunction and NLRP3 inflammasome activation. doi.org/10.1167/iovs.6…

Nicolas A. Yannuzzi et al. from the Bascom Palmer Eye Institute compare the antimicrobial efficacy and ocular surface toxicity of povidone-iodine (PI) and chlorhexidine gluconate (CHX) against clinical endophthalmitis isolates. doi.org/10.1167/iovs.6…

Deqiang Zheng et al. from Capital Medical University use whole-exome analysis to identifies candidate genes associated with diabetic retinopathy. doi.org/10.1167/iovs.6…

Eyvind Rødahl et al. from the University of Bergen identify and characterize a novel gene variant associated with late-onset, non-syndromic retinitis pigmentosa. doi.org/10.1167/iovs.6…

Xiaodong Sun, Bo Yu et al. from Shanghai General Hospital find that enhanced endocytosis and mitochondrial stress underlie severe retinitis pigmentosa with RHO P347L mutant. doi.org/10.1167/iovs.6…