

Ahmed Ismail, MD
249 posts

@A_Ismail_MD
IM PGY-1 @EVMSedu @ODU | Former Research Fellow @ONealCancerUAB & @NUFeinbergMed 🇺🇸 | MD @CairoUniv 🇪🇬



I had the pleasure of presenting my work at the AACR Annual Meeting 2026 and connecting with colleagues interested in hematology/oncology. Grateful for the opportunity to share my research and learn from leaders across the field.








Check out our recent analysis @OncJournal under mentorship of @ADesaiMD of 653 solid tumors evaluating HER2 by IHC, CNV & mutational profiling. 📊 Results: •IHC+: 3+ (3.1%), 2+ (13.2%), 1+ (19.8%), 63.9% neg •CN amplification: 3.1% (75% IHC3+) •Pathogenic ERBB2 mutations: 3.1% (only 5% IHC3+) 🔑 ERBB2-mut tumors rarely show IHC3+/CN amp → highlights need for comprehensive genomic testing. 💡 In the era of pan-tumor T-DXd approval, integrating genomic + phenotypic data can refine patient selection & advance precision oncology. @ONealCancerUAB @MehmetAkce2 @YanisBoumberMD @BasselElRayesMD @SylvesterCancer @HemOncMiami @carisls










🚨 Just published! @FrontOncology Our review on HER2-altered #NSCLC — from biology 🧬 & testing to latest therapies 🔗 bit.ly/HER2NSCLC 🔑 #biomarker testing: tissue and #ctDNA 💥 ADCs & TKIs: T-DXd, zongertinib, A166, ARX788 📈 Future: combo trials & next-gen agents With @A_Ismail_MD @YanisBoumberMD @OncoAlert @oncodaily @LungCancerRx @OncBrothers @HemOncFellows @HendriksLizza