Aedas

Re pinning. The corn bots found it. Im so tired.... The golden age. May the odds be forever in your favor. *sigh youtube.com/playlist?list=…

@Doze_1202 Sending hugs. youtu.be/UPbD6LScZLY?si…

Can I get some prayers, please? I’m not doing mentally well today. Something’s been bothering me

This is how they map your BioSignals to file formats & applications for later Manipulation and Control BioSignals are digitized into numerical data formats for storage (using binary structure 1's & 0's) pluto.bio/resources/Lear… Biological signals are not directly converted into standard computer binary files; rather, they are digitized into numerical data (often using binary representations like 0s and 1s) for storage in formats such as FASTQ, BAM, or VCF used in high-throughput research. pmc.ncbi.nlm.nih.gov/articles/PMC62… Digitization Process: Biological signals, which operate via binary-like active/inactive states (e.g., gene activation or protein switching), are measured and represented using mathematical structures suitable for digitization and exact representation by modern computers. Storage Formats: These digitized signals are stored in specific binary file formats like BAM (binary compressed sequence alignment) or FASTQ (raw sequence data and quality scores), which are computer-readable but not directly human-readable. pmc.ncbi.nlm.nih.gov/articles/PMC79… Direct Encoding: In advanced research, digital binary data can be directly encoded into the genomes of living cells (e.g., using CRISPR arrays and electrical signals) to create "living hard drives," but standard binary files on computers remain distinct from the biological material itself. webopedia.com/definitions/bi… While biological systems utilize binary logic for signal propagation (active vs. inactive), the creation of standard binary files requires converting these signals into numeric codes that computers can process and store. pmc.ncbi.nlm.nih.gov/articles/PMC85… File Formats FASTQ FASTQ is a text-based bioinformatics file format used to store nucleotide sequences along with their corresponding per-base quality scores, serving as the de facto standard for raw output from high-throughput sequencing instruments like the Illumina Genome Analyzer. Checking & Manipulating FASTQ Files homer.ucsd.edu/homer/basicTut… BAM (Binary Alignment Map) support.illumina.com/help/BS_App_RN… The BAM (Binary Alignment Map) format is the lossless, compressed binary representation of the Sequence Alignment Map (SAM) format, designed to efficiently store aligned sequencing reads up to 128 Mb. help.basespace.illumina.com/files-used-by-… Variant Call Format (VCF) Files gatk.broadinstitute.org/hc/en-us/artic… Variant Call Format is a standardized bioinformatics text file used to store DNA sequence variations, such as SNPs and indels, developed by the 1000 Genomes Project and currently in version 4.5. support.illumina.com/help/BaseSpace… ArtificialFastqGenerator ArtificialFastqGenerator takes a reference genome in FASTA format as input and outputs artificial FASTQ files. Since the artificial FASTQs are derived from the reference, the reference provides a gold-standard for the variant calling, so enabling evaluation of the pipeline. The user can customise DNA template/read length, gap size between paired-end reads, target coverage, whether to use quality scores taken from existing FASTQ files, and whether to simulate sequencing errors. github.com/mframpton/Arti… Then they map your biological information to applications via Reactome. Reactome is integrated into various applications primarily through its REST-based Analysis Service and Diagram Viewer APIs, allowing developers to embed pathway analysis and visualization directly into third-party software pipelines reactome.org/dev/pathways-o…

Pam Bondi is getting fired because the DOW is not 50k

One of my crazier undeveloped conspiracy theories is that Candy Crush was the first new-age WMD deployed on the masses to turn brains into pudding using repetition and optogenetics. I can always tell when someone has played a lot of Candy Crush.

Is @elonmusk still pretending the war is not happening?

Trump has 3 days to wage war Few understand this

RUSSIA IS SET TO SEND A SECOND FUEL-CARRYING SHIP TO CUBA.

These are all residential buildings.

🚨‼️ BREAKING 💥 Urgent: The final execution of over 10,000 Palestinian prisoners in Israeli occupation prisons has begun; we learn this with profound sadness.

@MrSausageGet @mcne73001

We just want to afford groceries.

BREAKING: Iran says any European country is welcome to make a deal to transit through Hormuz Strait.