AggarwalLab

Avengers! Assemble... alkyl phosphonates. Check out our new @angew_chem paper for the direct C(sp3)–H phosphonylation of unactivated alkanes ⚗️ Using an iron photocatalyst. Congrats Team! onlinelibrary.wiley.com/doi/10.1002/an… @BristolChem #photocatalysis

Our latest work with @duarte_group shows the unexpected exo-C2 lithiation of ABP and ABH, allowing access to ring-opening products with full stereocontrol. Congrats Team! #OrganicChemistry #StrainRelease @BristolChem pubs.acs.org/doi/10.1021/ja…

🎉 Chuffed to see our JACS paper is among the most read articles this month! See how a boron-mediated Ni/photoredox strategy for hydroalkylation of olefins enabled the access to quaternary carbons. pubs.acs.org/doi/10.1021/ja… Congrats Team! #Photoredox #Organoborons @BristolChem

Mixed emotions… 😊 Proud that Dr. Liang Wei is starting his independent career at Huazhong University of Science and Technology 🇨🇳✨, but sad to say goodbye to one of the kindest and brightest postdocs in the Aggarwal Lab. All the best, Liang! 🚀

Au revoir, auf Wiedersehen, arrivederci! 👋 Time flies✈️,our three visiting researchers are now back to their home universities to continue their research journeys. All the best to @GrossAdrien5 (🇫🇷 → Uni Freiburg 🇩🇪), Fin (Uni Hannover 🇩🇪), and Federica (Uni Pavia 🇮🇹)!

Breaking the rule-of-five in [2+2] cycloadditions!⚡ Check out our @NatureSynthesis article where a radical stabilization strategy enabled Photo EnT route to elusive 3D-isosteres of 6 membered N-heterocycles. nature.com/articles/s4416… #Photocatalysis #bioisosteres @BristolChem

The Bristol Synthesis Meeting is back! 📅 31 March 2026 Enjoy engaging and insightful chemistry talks from our esteemed guest speakers this spring. The deadline for registration is 20th March 2026. @LeonoriLab @BalskusLab @dixon_group @Huckgroup @BristolChem @DonnaBlackmond

🎉 Huge congratulations to Hanwen on successfully defending his PhD thesis! He is now Dr. Zhang (张瀚文). Wishing you all the best to your future career!

We skipped the year 2025, but Boron + Ir skipped dienes! Check out Liang and Zhouwen’s @J_A_C_S paper: pubs.acs.org/doi/10.1021/ja… ...to see how to access skipped 1,4-dienes enantioselectivity. Congrats to the team! 🎉 @BristolChem #Organoborons

🌊🧪 Ready for the sequel of our marine polyketide study? ✅ Bioactivity & chemogenomic profiling ✅ Ultra-high-res. NMR ✅ Modular total synthesis ➡️ Caylobolide B unlocked! doi.org/10.1002/anie.2… Superb collaborative effort with the Luesch and Butts groups. @BristolChem

Congratulations to Tom on successfully defending his thesis! He is now Dr. Plowright. Wishing him all the very best in his future career!

🚀Organoboron update! Shubham, Tapas, and Hong-Cheng dive into 'Recent Advances in Stereospecific Transformations of Organoboron Reagents.' Now out in the new open-access journal Transformative Chemistry. onlinelibrary.wiley.com/doi/10.1002/tc…

⚛️ When Ir meets boranes, chemistry hits different! Now in @J_A_C_S: Our Ir-catalyzed allylation via intermolecular 1,4-boronate rearrangement enables enantioselective access to (R)-pyricuol in 2 steps. 🎉 Congrats Team! 🔗 [pubs.acs.org/doi/10.1021/ja…] @BristolChem @bobbypaton

🎉 Huge congratulations to Dr. Malcolm George on successfully defending his PhD thesis! He’s now joining Pharmaron as a Senior Scientist in Process Chemistry. Wishing him every success in this exciting new chapter! 👏

💍 Looking for a ring? try one with Bpins! Check out our intramolecular lithiation–borylation route to 1,3-bis-boronic ester carbocycles, now out in @angew_chem. Congrats Chris and team! 🔗onlinelibrary.wiley.com/doi/10.1002/an… In collaboration with @merckgroup. #Organoborons @bristolchem

🌊 From a marine sponge to @angew_chem Novit! Mycapolyol E: fully synthesized and structurally confirmed via boronic ester homologation. 20 steps (LLS). 12 stereocenters. Congrats @sheenagh_aiken, @DylanRigby6 & team! 🔗 dx.doi.org/10.1002/anov.7… @BristolChem #TotalSynthesis

@BristolChem #NaturePaper #Boronchemistry

🌪️🔥🌊🌍 Mastering all four? We did it with alkenes! Our @Nature paper with @bobbypaton lab reveals a modular boron-mediated strategy solving the long-standing challenge of accessing tetrasubstituted alkenes with full stereo-control. Congrats team! nature.com/articles/s4158…

Radicals, tamed! Our new @J_A_C_S paper reveals an in situ doublet-state photocatalyst rivaling top photoreductants—enabling borylations & more. Huge congrats to the team! 🎉 #photocatalysis @BristolChem pubs.acs.org/doi/10.1021/ja…

Congratulations to Hannah on successfully defending her thesis! She is now Dr. Han. Wishing her all the best!