Alok Jha

My recent publication in Molecular Medicine “A novel CD112-derived peptide targeting gut-primed neutrophils to attenuate deadly hepatic injury”. link.springer.com/article/10.118…

New Research: B-1a cells mitigate radiation injury by protecting intestinal barrier integrity frontiersin.org/articles/10.33… #FrontiersIn #Immunology

@AlokGene @NorthwellHealth DLL4+ neutrophils promote Notch1-mediated endothelial PANoptosis to exacerbate acute lung injury in sepsis

Can we disrupt the amplification of systemic inflammation in #sepsis? Alok Jha @AlokGene, Ping Wang & team @NorthwellHealth find a unique neutrophil subpopulation expressing high DLL4 induces pulmonary endothelial cell PANoptosis, exacerbating acute lung injury. And treatment with a notch inhibitor in septic mice… 👇 doi.org/10.1172/JCI194… Image (1/2) shows mouse lung tissue with elevated damage (indicated by ZBP1, red) in tissue from sepsis mouse models with DLL4+ neutrophil injections; and survival rates (2/2) in septic mice following treatment.

My recent publication in “The Journal of Clinical Investigation (JCI)” “DLL4+ neutrophils promote Notch1-mediated endothelial PANoptosis to exacerbate acute lung injury in sepsis”. jci.org/articles/view/…

My recent publication in Nature Communications “ Gut-primed neutrophils activate Kupffer cells to promote hepatic injury in mouse sepsis” nature.com/articles/s4146…

I thought Time could be more than just one way-flow. Here Scientist Proposes ‘Three-Dimensional Time’ Theory. studyfinds.org/scientists-pro…

My recent publication in Molecular Medicine “The role of an anti-inflammatory molecule AIM/CD5L in gut ischemia/reperfusion injury of male mice.” molmed.biomedcentral.com/articles/10.11…

@NobelPrize Congratulations.

BREAKING NEWS The 2025 #NobelPrize in Physiology or Medicine has been awarded to Mary E. Brunkow, Fred Ramsdell and Shimon Sakaguchi “for their discoveries concerning peripheral immune tolerance.”

My recent publication in “Advanced Science”- “Critical Role of IL1R2‐ENO1 Interaction in Inhibiting Glycolysis‐Mediated Pyroptosis for Protection Against Lethal Sepsis” - Advanced Science - Wiley Online Library advanced.onlinelibrary.wiley.com/doi/10.1002/ad…

@EyeDaisyShu @MetabolitesMDPI @lennikov @MengluYangMD @gammaDave1 Congratulations.

Wow! This news made my day! Thank you so much @MetabolitesMDPI for the Best Paper Award! This review covers the role of oxidative stress in eye diseases, covering the front to back of the eye! Read the review here: mdpi.com/2218-1989/13/2… @lennikov @MengluYangMD @gammaDave1

@ClaireMax Great!

Dressed to match my labubus

My recent publication “Identification of a multiple DAMP scavenger mimicking the DAMP-binding site of TLR4 to ameliorate lethal sepsis” frontiersin.org/journals/immun…

New Research: Identification of a multiple DAMP scavenger mimicking the DAMP-binding site of TLR4 to ameliorate lethal sepsis frontiersin.org/articles/10.33… #FrontiersIn #Immunology

@EyeDaisyShu @ASIPath @WomeninPath @UNSWoptomvsci Congratulations!

I am so honoured to be a recipient of the ASIP Monga Family Junior Faculty Scholar Award! Thank you very much to the American Society for Investigative Pathology and congratulations to all the awardees! @ASIPath @WomeninPath @UNSWoptomvsci #UNSWScientia

@EyeDaisyShu @ASIPath @WomeninPath @AmyEngevik @micromindy @MengluYangMD @thekengevik Great!

Reunited with the famous Engevik sisters at #asip2025! 😍🙌 @ASIPath @WomeninPath @AmyEngevik @micromindy @MengluYangMD #pathobiology2025 missing you @thekengevik

@AlokGene Day 3 | World Governments Summit 2025 – Ministerial meetings, future solutions, and exceptional opportunities for governments. Global leaders are presenting new insights. Join the Conversation. #WorldGovSummit #WGS25

@AlokGene Day 2 | World Governments Summit 2025 – Discussions happening now! Artificial intelligence, government efficiency, and emerging economies. Join the Conversation. #WorldGovSummit #WGS25

@AlokGene Day 1 | World Governments Summit 2025 | More than 30 heads of state and government, 400 ministers, and top global business leaders are gathering to envision a better future for humanity. Join the Conversation. #WorldGovSummit #WGS25

@AlokGene You're now set to receive daily insights as we gear up for #WGS2025 Stay tuned for key discussions on Shaping Future Governments Feb 11-13, Dubai, UAE | Join the Conversation! #WorldGovSummit Reply #Stop to opt-out