Angelo Frei, PhD

And it is LIVE! The Frei Lab website is now online! Took quite a bit longer than expected but quite happy with the result. More coming soon! (Special thanks to @dsquintana for his tutorials on how to make academic websites with R-Studio, highly recommend it) #chemtwitter #newPI

@andrewwhite01 Gonna cheeky self-nominate. We do modular metal complex synthesis for the development of novel antibiotics. We done some initial ML approaches doi.org/10.1002/anie.2… and using robotics to automate synthesis: doi.org/10.1038/s41467…. Been playing around with Edison quite a bit!

Who are great young investigators doing AI in chemistry and automation in chemistry? I occasionally get asked for young people in the field and all the people I know are getting old. Feel free to self-nominate

I believe this will also be my last post on this platform. From next year the account will go dormant. Connect with me on LinkedIn or Bluesky!

Paper: lnkd.in/eeYxcFJD Behind-the-Paper: lnkd.in/esC89XBX

Our work on high-throughput synthesis of triazole-based metal complexes is out now in @NatureComms! Link for Paper and Blog Post by Postdoc David who did the bulk of the work below.

Robotic system synthesizes hundreds of metal complexes to find potential new antibiotic phys.org/news/2025-12-r…

High-throughput triazole-based combinatorial click chemistry for the synthesis and identification of functional metal complexes nature.com/articles/s4146…

New Antibiotic Candidates Emerge from Robotic Synthesis of Metal Complexes This rapid screening process identified an iridium-based #antibioticcandidate that shows promise in human cells to kill #bacteria while remaining nontoxic @Angelo_Frei @UniOfYork hubs.ly/Q03YX-QP0

@chemFunMan @UniOfYork @ucdchemistry @ucddublin @NadiaElgho @anbeirneach @QuinnGroupUCD Thanks for the great hospitality and interesting conversations!

Welcome @Angelo_Frei 🇨🇭from @UniOfYork to @ucdchemistry @ucddublin in his maiden visit to Dublin 🇮🇪 giving us a great talk and exchanging with students and academics 😎🤓🪴

@jaleixoaf Thanks José and I am sorry for your loss. It was good to see you in Florence last week!

@Angelo_Frei Very nice video! I Lost my dad because of bacteria resistance as he was a transplanted patient. Wishing you the best in your research!

After 2 years of work, our flashMOOC about metal-based antibiotics is now out! The goal was to make an accessible video about the urgent problem that is antimicrobial resistance and how metal complexes could be part of the solution. (Video below)

After 2 years of work, our flashMOOC about metal-based antibiotics is now out! The goal was to make an accessible video about the urgent problem that is antimicrobial resistance and how metal complexes could be part of the solution. youtube.com/watch?v=MgJq6c…

🚨 PhD Opportunity @UMU! Join a 4-year funded FPI project on light-activated metallodrugs for cancer therapy. Start: Jan 2026 | Deadline: Oct 15, 2025 📧 Contact: jruiz@um.es 📎 PDF attached – official link coming soon! #PhDOffer #CancerResearch #FPIContract #UMU #ChemistryJobs

👩‍🔬 We trained a deep learning model to create a new platinum complex. It works. Our latest research, “Overcoming Cisplatin Resistance via Deep Learning–Assisted De Novo Design of Platinum Complexes,” is now live on ChemRxiv! Link in comments 👇 #AI #Oncology #Metallodrugs

Fully funded postdoc position available at beautiful Okinawa 🪸🐠 Starting September, 2025 or earlier or later 🗓️ If you're interested in organometallic chemistry and catalysis, please contact me 📨 oist.jp/careers/postdo…

Robust SMILES for transition metal complexes? Yes! 👇 jcheminf.biomedcentral.com/articles/10.11…

@chemhsun @J_A_C_S That is a great cover!

What a fantastic Cover Art (for the fight against antimicrobial resistance (AMR) in @J_A_C_S , #MyACSCover! Thanks Mr. Li Zhang and Dr. Chenyuan Wang for designing the cover image! Please download the paper (open access) for details at pubs.acs.org/toc/jacsat/147…

Some of our poster-prize winners & talk-givers #Dalton2025: Frei, Lynam, Slattery, Douthwaite, Fairlamb, Parker, Willans, Weller labs. Nat. Baranska Alex Watson Jake Walder Sara Bonfante Rebecca Willans Kris Altus Katie Keating Chloe van Beek Stefan Flesch Anson Chau Cagri Ozsan

***For candidates with a background in organometallic chemistry***, there is a postdoctoral position in bioorganometallic chemistry currently available in my lab @inrsciences. Interested candidates may submit their application by email at annie.castonguay@inrs.ca.

We are incredibly proud to share this groundbreaking work! Our latest publication, "Leveraging Immunogenic Cell Death to Enhance the Immune Response against Malignant Pleural Mesothelioma Tumors" in JACS, showcases the remarkable potential of novel Au(III) complexes to induce long-lasting antitumor immunity. It is a true testament to the power of innovative science and teamwork. 💪 Read the full paper here: pubs.acs.org/doi/10.1021/ja…