
@askrenal
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@askrenal
@askrenal
Crowdsourcing answers to Nephrology questions! A @nephjc initiative, based @UAlberta #Academic a/c. Bot Questions? DM - @dr_nikhilshah



#askrenal @askrenal @BradRovin @kidneydoc101 refractory LN. A young F treated with MMF for class III. Worsening crea on repeat bx IV with crescents. Received CPD, than MMF, after 12 mo again worse - bx active IV. We either have ritux or anifrolumab available. How would you treat?

@kdjhaveri @SaynaNorouzi @askrenal @DMalieckal Eculuzumab but not avacopan has been used with uncertain benefits added to SOC. Complenent activation and MAC fornafion are involved in glomerular injury.

Question for #NephX #NephTwitter - CajinaCarmen: 🚨🚨🚨 Looking for some help -When you suspect 5-oxoproline AGMA, do you go with urine or serum 5-oxoproline? Or both? Do you usually check glutathione too? #NephTwitter #Nephrology #MedEd #askrenal @as… twitter.com/CajinaCarmen/s…

🚨🚨🚨 Looking for some help -When you suspect 5-oxoproline AGMA, do you go with urine or serum 5-oxoproline? Or both? Do you usually check glutathione too? #NephTwitter #Nephrology #MedEd #askrenal @askrenal

Have folks used avacopan in anti GBM disease? #askrenal @askrenal @DMalieckal

@DrPallaviPrasad @askrenal But yes, mam. I guess AAV or LN in remission could still progress to CKD. Apparently, even Bartter’s syndrome has a risk of progression to ckd. pmc.ncbi.nlm.nih.gov/articles/PMC10… Even the so called benign haematuria (TBMN) have shown progression to CKD 🙄 pubmed.ncbi.nlm.nih.gov/30687875/

@DrPallaviPrasad @askrenal A disease like Thin Basement Disease, though has abnormalities on histology and persistent haematuria, technically come under CKD but is not going to be progressive so in that case is the CKD term necessary here?

@DrPallaviPrasad @askrenal According to definition that's a clear yes mam. But I'm just worried about the tag/brand of ckd on them if it's really required. If it's going to be progressive it's fine, but some conditions are really non progressive and why should they be branded as ckd?

@diplomaticdoc @askrenal The G1A1 just helps to classify them as low risk...but not "no risk"

5 cases of amyloid in 2 days r too much for a small vol. kidney bx centre. Age-20to 68. 4: SAA+, 1:light chain restricted.Beware.This innocent material is causing much harm! It can be subtle as in our previous post. #RenalPath #AskRenal #Nephtwitter #RenalPathSociety #Pathtwitter