TK Kozai (BIONICLab.org)

Grateful for this unexpected feature. I still have imposter syndrome days... I thought that was supposed to en be after tenure?

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Review: lnkd.in/edpJ2zzy | Fatigue: lnkd.in/egAwPGv | Drugs: lnkd.in/eyNPriA9

🚌 Every neuroscience textbook says myelin speeds up nerve conduction. That is correct. It is also incomplete in a way that has misled the BCI field for years. 🧵

🛠 Recording failure and stimulation efficacy loss are two expressions of one underlying problem. Adaptive stimulation and next-gen electrodes must be calibrated to the chronic trajectory. sciencedirect.com/science/articl… #UPNExT #BCI #ICMS

🧬 Neurovascular coupling globally recovers, but local coupling near the probe stays attenuated. This focal metabolic deficit is the same biology that drives recording failure. Vascular remodeling, myelin damage, autophagy-lysosomal dysfunction, impaired metabolic clearance.

🧠 Visual cortex prostheses use 25-Hz ICMS to evoke phosphenes in blind patients.New UP NExT paper in Biomaterials: in awake mice, 25-Hz ICMS preferentially induces chronic epileptiform events that emerge wks after implantation and acute testing cannot detect.

📊 Every computer, smartphone, TV, medical device, car, satellite, and AI system on Earth runs on the electron. Thomson wasn't inventing any of it. He wanted to know what cathode rays were. Basic research answers questions before anyone knows they matter. #YourTaxDollarsAtWork

💡 1947: transistor. 1958: integrated circuit. 1971: microprocessor. 2024: $628B semiconductor industry, projected to pass $1T by 2030. 1 trillion chips shipped in 2024. Top 10 chip companies: $9.5T market cap. All from controlling the particle Thomson found in a glass tube.

⚡ In 1897, J.J. Thomson shot electricity through a glass tube and found particles 1,000x lighter than a hydrogen atom. He called them "corpuscles." His colleagues thought he was joking. He had discovered the electron, the first subatomic particle in history. Nobel Prize, 1906.

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| Lysosome: lnkd.in/eEraH5Fv | Lipofuscin: lnkd.in/g6vNw8NP | Metabolic: lnkd.in/eZ_7ZsTN

🗑️ Every neuron in your brain has a waste management system. When it fails near a chronically implanted electrode, the cell does not die immediately. It accumulates damage quietly, for weeks, before it shows up in your recordings. 🧵