Bruce Levine, Ph.D. 🇺🇦🥼🔬🧬🧪💉

🎙️Excited to announce the website for Ring That Bell 🔔 which I co-wrote w internationally acclaimed Irish country music artist @mags__mccarthy. It tells the emotional story of a cancer patient facing relapse and the fierce advocacy, support, and groundbreaking science that offer new hope. #cancer #cancerresearch #immunotherapy #hope ringthatbellsong.com

Why should you comment on OMB Proposed Rule OMB-2026-0034? Submit comments before the Monday July 13 1159PM deadline here federalregister.gov/documents/2026…

More evidence for GPNMB as a tumor target from Shiela Singh & colleagues -Dual tumour–myeloid targeting of glioblastoma with GPNMB CAR-T cells @Nature Both reports pre-clinical, but the convergence is hard to ignore for the next CAR T to target solid tumors in clinical testing. nature.com/articles/s4158…

🧵/1 AI-driven discovery of GPNMB CAR T cells as a multi-cancer therapy @CellPressNews AI did not “invent” a CAR T therapy here. It helped focus the search for a plausible target in a very large haystack of public single-cell and expression data. That distinction matters. The important advance is human expertise plus AI triage, followed by wet lab validation. GPNMB CAR T activity across melanoma, leukemia, and colorectal models is intriguing. The hard human enabled part is demonstrating specificity, safety, clinical translation. @PennMedicine @daniel_baker_j @JonEpsteinLab @AranyLab @carlhjune

There is now no living person using an iron lung Because vaccines work ktla.com/news/last-amer…

What makes an effective public comment? A public comment is not a vote and is not politically adversarial in tone. Agencies are not supposed to finalize a rule simply because more people support or oppose it. The most effective comments become part of the rulemaking record because they offer facts, expert judgment, concrete examples, data, legal or policy concerns, and workable alternatives. The Federal Register’s rulemaking guide explains that agencies must base their final reasoning on the rulemaking record, including comments, scientific data, expert opinions, and facts; persuasive new data or policy arguments can lead an agency to change or even terminate a rulemaking. For the OMB proposed rule on federal financial assistance, comments are due July 13, 2026. OMB specifically asks commenters to identify the section of the regulation being addressed by beginning each comment with the relevant section number in brackets, such as [200.205]. Direct comment submission page: regulations.gov/commenton/OMB-…

My comment submitted in response to OMB Proposed Rule OMB-2026-0034 #OMB #NIH #Science 🧵/7 of 7

My comment submitted in response to OMB Proposed Rule OMB-2026-0034 #OMB #NIH #Science 🧵/1 of 7

🚨Alarm bells for science in the USA - the administration is trying to cement political control over research funding, publication and presentation of research findings. Medical progress depends on independent expert led research and the ability to share that research with the scientific community and the public.

This book is hilarious and on point. Instead of cliché positivity affirmations, it is a collection of sarcastic and realistic affirmations. Here are 10 of my favorites:

In hallways and on sidewalks, who has wished for phone reading lanes for the distracted?

Saw Decision Day over the weekend and I have a question. If they were/are so smart and capable of interstellar travel, why do they keep crashing their ships?

@bradloncar Thank you for highlighting 🙏

As NIH Director for over six years, Dr. Zerhouni is the perfect speaker to share thoughts on the critical role government plays in investing in science, and explaining the importance of it to the American public.

🚨👇Clinical fellows interested in cell and gene therapy applications #celltherapy #genetherapy #immunotherapy #cancer #autoimmune #hemoglobinopathies

#NIH 🧵