Bastien Rioux

@PargolBalali Read the related editorial by @B_Rioux and Whitelely: neurology.org/doi/10.1212/WN…

:-) annerowlingclinic.org/about/news/bas…

Polygenic Risk Scores to Investigate the Genetic Liability to Poststroke Epilepsy In this #BloggingStroke post, @B_Rioux discusses #Stroke article by @SanticlocMD & @CyprienRivier et al. #AHAJournals ahajournals.org/do/10.1161/blo…

Anti-Inflammatory Therapy for Cerebral Small Vessel Disease: Genetic Evidence for Potential Druggable Targets In this #BloggingStroke post, @B_Rioux discusses #Stroke article by Sun et al. #AHAJournals ahajournals.org/do/10.1161/blo…

What’s in a Predictor? The Case of Brain Imaging Markers for Poststroke Cognitive Impairment In this #BloggingStroke post, @B_Rioux discusses #Stroke article by Hassani et al. #AHAJournals @CBushnellMD @LBGoldsteinMD ahajournals.org/do/10.1161/blo…

In this Blogging stroke, I discuss MRI "predictors" of cognitive function after stroke and explain why they are difficult to interpret clinically. "Risk estimations in the clinic — including intuitions or ‘gestalt’ — are inherently multivariable." ahajournals.org/do/10.1161/blo…

Can Proteomic Profiling Help Predict Incident Ischemic Stroke in the General Population? In this #BloggingStroke post, @B_Rioux discusses #Stroke article by Gan et al. #AHAJournals ahajournals.org/do/10.1161/blo…

Research by @HuntLabEdin & @DrMcglasson (UK DRI at Edinburgh) sheds light on the mechanisms behind RVCL-S, a rare genetic disorder that affects small blood vessels. The study identifies an important therapeutic target👉 buff.ly/QwmdOV5

Our work led by Sarah McGlasson and colleagues from the Hunt lab at UK DRI Edinburgh sheds light on a rare genetic disease caused by DNA damage in small blood vessels Powerful translational approach using UK Biobank and mechanistic studies on TREX1 ukdri.ac.uk/news-and-event…

Are Neuroinflammation and Blood-Brain Barrier Dysfunction Involved in Cerebral Microbleeds? In this #BloggingStroke post, @B_Rioux discusses #Stroke article by @Lupei_Cai et al. @CamStroke #AHAJournals ahajournals.org/do/10.1161/blo…

Can Serum Biomarkers Help Detect Hemorrhagic Transformation After Intravenous Thrombolysis in Acute Ischemic Stroke? In this #BloggingStroke post, @B_Rioux discusses #Stroke article by Guo et al. @NguyenThanhMD #AHAJournals ahajournals.org/do/10.1161/blo…

Can Age-Stratified Genetic Analyses Help Identify Risk Factors for Stroke in Younger Adults? In this #BloggingStroke post, @B_Rioux discusses #Stroke article by Nguyen et al. #AHAJournals ahajournals.org/do/10.1161/blo…

Can Age-Stratified Genetic Analyses Help Identify Risk Factors for Stroke in Younger Adults? ahajournals.org/do/10.1161/blo…

Sex-Specific Genetic Association Studies Help Uncover Stroke Mechanisms In this #BloggingStroke post, @B_Rioux discusses #Stroke article by @JaraCarcel et al. @ArenillasJF @brainbleedmd @FabregaGallego @MarFreijo @vobach3 @israelcadenas1 #AHAJournals ahajournals.org/do/10.1161/blo…

Nouvelle/new publication!👇 cambridge.org/core/journals/… DIDO times in Québec and clinical outcomes among EVT-treated pts. 🧠 Great work from Dr Joel Neves Briard, Aymen Sahal, colleagues from all EVT sites in QC and @INESSS_Qc @INR_CHUM

Early Direct Oral Anticoagulant Initiation is Generally Safe in Ischemic Stroke Associated With Atrial Fibrillation In this #BloggingStroke post, @B_Rioux discusses @TheLancet article by Werring et al. on the OPTIMAS trial. @BoNorrving ahajournals.org/do/10.1161/blo…

Did you know 300 million people live with a rare disease worldwide? This #RareDiseaseDay, we're spotlighting @HuntLabEdin (UK DRI at Edinburgh). The lab is researching a gene called TREX1, which when faulty, causes 2 different rare brain diseases 🧬 🧠 🎥 @DrMcglasson explains ⬇️

Great study on plasma p-tau217 in cognitive impairment from an international collaboration involving researchers at @mcgillu alz-journals.onlinelibrary.wiley.com/doi/full/10.10…

2/2 New mechanistic discoveries will be facilitated through a shift towards biologically-derived phenotypes, age-stratified analyses and inclusion of diverse ancestry populations.

1/2 Excellent review by John Hardy (UK DRI at UCL) on the genetic architectures of neurodegenerative diseases and how our current understand of failing damage clearance systems can inform future GWASs. #Sec11" target="_blank" rel="nofollow noopener">nature.com/articles/s4138…