Bai Lab PSU

The entire Bai lab attended @ASBMB Transcriptional Regulation. We were so excited to present posters and to hear Lucy give a talk!

Our meeting on transcriptional regulation is underway! Next up: a session on #chromatin, genome architecture and remodelers. asbmb.org/meetings-event… #RNA #ASBMB

Exciting news! 🎉 @lab_poirier and @rcollepardo have curated an amazing @MGO_BPS program for the 2025 BPS Meeting! Featuring top speakers like @seresanu, @BaiLab_PSU, @McGintyLab, @AnnaPanchenko13, Shoji Takada, and Marcus Woodworth from @Melike_Lak. Don’t miss it! 🚀✨ #BPS2025

We are hiring! The Department of Biochemistry and Molecular Biology at Penn State ⁦@BMB_PSU⁩ invites applicants for multiple tenure-track Assistant Professor positions in the broad areas of genetics, cell and developmental biology! Check us out! psu.wd1.myworkdayjobs.com/en-US/PSU_Acad…

@TracyLangkilde Thank you!!

@BaiLab_PSU Congratulations!

Out now in Molecular Cell! Along with Tan and Mahoney labs, we combine cellular, in vitro, and computational methods to understand how sequence features affect pioneer factor specificity (cofactors play a big role) doi.org/10.1016/j.molc…

@KellerCaponePhD Thanks Cheryl!

@BaiLab_PSU Congratulations! 🎉

@ADhasarathy Thank you!

This work was led by bai lab students Cheng Xu (now a postdoc with @JefBoeke) and @hekleinschmidt (grad student @BMB_PSU).

Very proud of this highly collaborative paper with the @mahonylab @RemoRohs and Gordân labs in which we explore how ApiAP2 transcription factors with similar DNA binding specificities define their target genes, a ubiquitous challenge in all cells! academic.oup.com/nar/advance-ar…?

Check out our new Pioneer Factor review! We present both sides of the debate about whether pioneer factors have unique properties among TFs tandfonline.com/doi/full/10.10…

Congratulations to the Bai lab's newest PhD Yi Li of @BMB_PSU! Yi's main thesis project was published today!

Check out our latest paper in @NatureComms where we develop a methylation-based sequencing assay to capture chromosomal interactions with a viewpoint nature.com/articles/s4146…

Bai lab PhD students James (@BMB_PSU) and Cheng (@huckinstitutes MCIBS) graduated yesterday! James has started as a biologist at @theNCI and Cheng is starting as a postdoc with @JefBoeke!

Check out our latest work in @eLife! This work, led by graduate student James (graduating Sunday) uses a range of techniques, including a new methylation-based method to dissect gene cluster in haploid yeast. doi.org/10.7554/eLife.…

Cheng's primary work is available currently as a preprint. Be on the lookout for more great work as Cheng transitions to a post doc very soon! biorxiv.org/content/10.110…

Congratulations to the Bai lab's newest PhD, Cheng Xu!

Excited to share my postdoctoral work is now online @CellCellPress thanks to all the coauthors that contributed to this work!

Congrats to the Bai lab's newest PhD! James passed his defense on Friday and is off to the NIH as a biologist!

Preprint now available: we investigated the binding specificity of pioneer factor FoxA1 by developing a high throughput synthetic approach ChIP-ISO. biorxiv.org/content/10.110…