Jonathan Cooper
1.5K posts
@Batten_PSDL
Leads the PSDL at Washington University School of Medicine, in St Louis working to understand and devise therapies for Batten Disease. Views are my own.
After a great trip to New Zealand visiting @NclSteph the @BDSRA 's Ineka Whiteman and Nadia Mitchell, today sees the start of NCL 2025. Plenty of PSDL presentations on our latest work, looking forward to seeing many colleagues & families #battendisease
CLN2 disease is a childhood-onset neurodegenerative lysosomal storage disorder caused by a deficiency of TPP1, but little is known about the cellular etiology. @Batten_PSDL @keigotakahashi6 @noahs_hope1 @washumedicine now reveal GABAergic interneurons contribute to the fatal seizure phenotype in CLN2 disease mice: insight.jci.org/articles/view/… The image shows widespread SCMAS accumulation (green) in Cln2R207X/R207X mice at 15 weeks.
Just in time for #RNA25, the Cottrell Lab has posted our first independent preprint to bioRxiv. This is the first first-author publication from graduate student Addison Young and the first publication for the four undergraduate co-authors. biorxiv.org/content/10.110… 1/2
BDSRA Canada, the BDSRA Foundation, and its Batten Disease Clinical Centers of Excellence applaud the British Columbia Government’s decision to reinstate funding for Charleigh Pollock’s life-sustaining enzyme replacement therapy, Brineura, to treat CLN2: ow.ly/798p50Ws62t
In today's #GrandRounds, Kennedy Krieger Institute's Erica Augustine, MD, MS, gave the 39th Annual Philip R. Dodge Lecture on neuronal ceroid lipofuscinoses or Batten disease. She discussed the history of Batten, disease onset timeline and the need for therapeutic innovations.
Check out the May Newsletter where we spotlight #WashUPhysicianScientist Dr. Patricia Dickson. She tells a great story! wustl.box.com/s/6mxo8t0jmogc…
🧬RESEARCH SPOTLIGHT 🧬 Dr. Jonathan Cooper and Dr. Ewa Ziółkowska will utilize their BDGRI research grant to explore why children with Batten disease have difficulty swallowing. Learn more about this project at the BDGRI website: battenresearch.org/funded-project… #BattenResearch
BREAKING: We are proud to announce the recipients of the Batten Disease Global Research Initiative inaugural Research Grant round. Learn more about the recipients and their research: ow.ly/380m50VjYlH #BattenResearch #BattenDisease #RareDisease #Science #Research #Grant
Greatly looking forward @washumedicine 's Rare Disease Day Symposium tomorrow. Some great speakers covering pre-clinical, translational and clinical research, but most importantly advocacy groups too #RareDiseaseDay (but a week earlier!)
Launching today on #RareDiseaseDay – RARITY (Research Alliance for Rare Illness Translational Pathways), a new research theme focused on translating rare disease research into real-world impact! Follow us to stay connected. #TogetherForRare #RARITYResearch
Tomorrow!
Congratulations to the 2025 #WORLDSymposia Young Investigator Award rcpts: Pratikshya Adhikari, Aimee Donald, Allan Feng, Angelica Maria Herreno Pachon, Andres Felipe Leal, Connor Lewis, Anna Reinelt, Krystyna Noelle Rytel, Roselena Schuh & Ewa Ziolkowska worldsymposia.org/worldsymposium…
RESEARCH UPDATES: Our Dr. Ineka Whiteman detailed two research highlights in her latest column, featuring @Batten_PSDL and @MCRI_for_kids: ow.ly/ckAe50USGJW #BattenAdvocatesForACure #BattenDisease #Research #CLN2Disease #CLN3Disease #Speech #Language #Science @WUSTL
