Aparna Bhaduri

@UCLA @biorxiv (5/5) Why it matters: In vivo ablation of NVP-associated programs remodels the tumor and significantly extends survival. These studies move us from descriptive atlases to a mechanistic, targetable understanding of tumor organization. Check them out!

@UCLA @biorxiv (4/5) Next: Meet the NVP (Neurovascular Progenitor) 🧬. This rare population co-expresses neural and perivascular programs. Using patient-derived lineage tracing, we proved NVPs can bridge the gap, giving rise to both neural and mesenchymal fates.

(1/5) How does glioblastoma maintain its immense heterogeneity? 🧠 Two new companion papers from the Bhaduri Lab @UCLA now on @bioRxiv offer a lineage-resolved view of GBM hierarchies. Let’s dive in! 🧵👇 biorxiv.org/content/10.648… biorxiv.org/content/10.110…

I'm incredibly proud to be a  part of the V Foundation's new PSA campaign because they’re 💯% in for Victory Over Cancer®! The V Foundation gives 💯% of every dollar donated directly to lifesaving cancer research—no exceptions. I'm so honored to be on this team!

@KonopkaLab Welcome to UCLA! Delighted to have you here!

Big news—we’ve moved to the David Geffen School of Medicine at UCLA! Even bigger: Gena is now Chair of the Department of Neurobiology. Congrats, Dr. Konopka! 💙🧠 #UCLA #Neurobiology #NewBeginnings

So excited to share this paper led by @ShivaniBaisi_MD! Check out iHOTT!!

A huge thank you to the amazing collaborators and members of the Bhaduri Lab for their contributions to this study! Antoni Martija, @prnano9, @Jalbsoto, Dan Jaklic, @MilJessenya, Rista White, @JacquiMMartn1, Dakshesh Rana, @GeschwindLab

Our findings suggest that the early entry of thalamocortical afferents in human and nonhuman primate cortex mediates communication with cortical progenitors. This demonstrates that the human thalamus actively sculpts cortical architecture during early development! 🧩

Excited to present our new preprint led by @claudianguyen95 uncovering how thalamic input shapes human cortical development! We discover that thalamic axons promote upper layer cortical neurogenesis through NRXN1-mediated contacts with outer radial glia. biorxiv.org/content/10.110…

📢 Paper out! FCDII is more complex than expected - somatic mTOR-activating mutations affect multiple cell lineages, yet only a fraction become cytomegalic. Dysmorphic neurons show mitochondrial dysfunction. #Epilepsy #BrainMosaicism #Neurodevelpment

@ArlottaLab Congratulations!! What amazing news!

Congratulations to Paola for being elected to the National Academy of Sciences! nasonline.org/news/2025-nas-…

A new UCLA study leverages computational methods and existing data to bring us closer to answering the question: How does the brain build itself? @dgsomucla @UCLAHealth @UCLAstemcell newsroom.ucla.edu/stories/crowds…

Parallel meta-analyses of the human cortex in development (seven datasets) and adulthood (16 datasets) generated over 500 gene co-expression networks describing of cortical development, centering on peak stages of neurogenesis @BhaduriLab @prnano9 nature.com/articles/s4159…