@BiVictriXTherapeutics

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@BiVictriXTherapeutics

@BiVictriXTherapeutics

@BiVictriX

Exploiting the Bi-Cygni technology, delivering a new class of biotherapeutics with superior selectivity. https://t.co/n0JxAV5xPV

Macclesfield, England Katılım Mayıs 2021
473 Takip Edilen188 Takipçiler
@BiVictriXTherapeutics
@BiVictriXTherapeutics@BiVictriX·
These compelling results demonstrate the potential of BVX002 to deliver meaningful efficacy where other B7-H4-targeted ADCs fall short. To read more about this study, visit our website.
@BiVictriXTherapeutics tweet media
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@BiVictriXTherapeutics
@BiVictriXTherapeutics@BiVictriX·
In a mouse unresponsive to AstraZeneca’s B7H4-TOPOi-based ADC, AZD8205, a single dose of BVX002 was not only able to reverse the exponential growth of the tumour but also resulted in tumour regressions of >62% in just 14 days!
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@BiVictriXTherapeutics
@BiVictriXTherapeutics@BiVictriX·
🚀 Exciting news from BiVictriX! Our lead solid‑tumour ADC, BVX002, has delivered tumour growth inhibition and regressions in an AZD8205-resistant mouse 🎯 New data shows that a single dose of BVX002 reverses tumour growth in an AZD8205-resistant mouse 🌟
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@BiVictriXTherapeutics
@BiVictriXTherapeutics@BiVictriX·
✅ Our Bi-Cygni® platform breaks through expression thresholds that limit conventional ADCs. 🧬 Precision, potency, and consistent DAR4 from our site-specific conjugation tech. We’re setting a new bar in #ADC innovation.
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@BiVictriXTherapeutics
@BiVictriXTherapeutics@BiVictriX·
🚀 Preclinical win for #BiVictriX: Our bispecific ADC, BVX002, outperformed 2 B7H4-targeted competitors (Pfizer’s SGN-B7H4V* & AZ’s AZD8205*) in head-to-head studies. 📊 Tumor regressions across all doses tested. 👇 More on why this matters:
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@BiVictriXTherapeutics
@BiVictriXTherapeutics@BiVictriX·
🔬 At BiVictriX, we’re not confined to 1 ADC design philosophy. Our BVX002 programme employs an innovative “AND/OR”-gated bispecific ADC to tackle ovarian cancer's tumour heterogeneity. It’s about clinically relevant solutions, not just being different. #ADC #bispecific #oncology
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@BiVictriXTherapeutics
@BiVictriXTherapeutics@BiVictriX·
Is the accepted dogma around the therapeutic window of #ADCs in need of a rethink? In their recent paper, Columbo and Rich highlight the mounting clinical evidence that suggests ADCs do not significantly increase the MTD of their conjugated drugs: cell.com/cancer-cell/pd…
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@BiVictriXTherapeutics retweetledi
LUKA GLOBAL GROUP
LUKA GLOBAL GROUP@lukaglobal·
Antibody drug conjugates: BiVictriX drives a new era in cancer medicine - zurl.co/ai4z
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