Dr. Brianne Barker

Was just looking at the @CellCellPress Table of Contents in my email and was baffled when I read the title of this paper. Then I realized that the second word was not “poutine”

@arman_sawhney That was basically my thought and the thought of another person I asked as well. My answer in the moment was “I don’t know, that’s a good question. Our peripheral tolerance mechanisms overlap central tolerance so hopefully peripheral tolerance would take care of it.”

@BioProfBarker This is a really interesting question. The combination of the immature B cells not recieving survival signals outside the BM plus any leaking immune cells not necessarily being connected to a broader circulatory/lymphatic network makes my gut answer not likely, but possibly?

My @DrewUniversity undergrads taking Immunology are asking some FANTASTIC questions this semester, so I thought I would start a thread for Immunologists to ponder and/or crowd source answers. #DrewU

Also “Are there any pathogens that have ubiquitin inhibitors to evade Class I?” The students were really on fire today

Another question today (and yes I know the answer to this one but I was still impressed by the question): wait, so if a self-protein got an amino acid change from a mutation like what would happen in a cancer cell, would that now be presented and act as a foreign antigen?

Another student came to my office after class to talk more about viruses and Class I. In part of our conversation, I suggested he look at @JonYewdell ‘s work on PubMed and he is so excited to spend the afternoon investigating some papers

Some of today’s fantastic questions (admittedly all answerable by thinking about pathogens as containing many epitope peptides or by thinking of MHC molecules presented by a cell as a population but cool nonetheless…)

From NJ

Amazing to join @profvrr @stephanielangel @CindyLeifer @BioProfBarker to talk sex-hormones & immunity, Life history theory and human systems immunology: microbe.tv/immune/immune-…

Dear Mammoths: I feel you. Each spring, it feels like hay fever will wipe me out too.

@seek4learning8 giantmicrobes.com/us/?gad_source… (they also have them on Amazon)

@BioProfBarker Gotta have this. Where did you get it?

Today’s star of Immunology class

My Fall 2024 Immunology Course has started and I finally worked out my tech issues so you can follow along here: youtube.com/playlist?list=…

Just figured out that the lecture videos I have been making this semester (aka Immunology Lectures 1-5 so far) have not been posting to YouTube like they are supposed to and are ending up somewhere in the ether. Awesome.

A definite perk of living in the future: can stream all the top college field hockey games from my couch. A highlight of my fall. Also, Go @DukeFH!

Went with same arm based on my memory of our discussion of @victora_lab’s work on #Immune and GC responses. Have also seen the earlier study that someone else mentioned here…and realistically, I probably over thought it

At CVS getting some vaccines. Pharmacist says I have to decide on arm while he preps the vaccine. Don’t think he realized he was talking to an immunologist who would put farrrrr too much thought into it. (What about that paper that said…)