Boccellato_Lab

We kicked off the week with an Impromptu Seminar by Francesco Boccellato (@Boc_Lab) on “mucosoids”, human stem-cell-based in-vitro equivalent of a mucosa to study epithelial homeostasis & responses to bacterial infections. Thank you, Francesco & host Adjunct PI Georg Busslinger!

🚨 We are hiring a #postdoc in Quantitative Cell Biology/Biochemistry. Join us if you are interested in using super-resolution STED & cryoET to uncover self- organization dynamics of cell interfaces & glycobiology collab. with WuLab Deadline 31 August nature.com/naturecareers/…

Check this out! 💥 #organoids #microenvironment #infection #LudiwigInstituteOxford ⁦@Boc_Lab⁩ Organoids and derived models to study the microenvironments of bacterial infections - ScienceDirect sciencedirect.com/science/articl…

@alinkmd Dear Alex, this is a terrible tragedy. My thoughts and heart are with the people of Magdeburg.

Horrific attack on #Magdeburg Christmas market! Likely many dead and injured... it could have happened to any of us! Our thoughts are with the injured and their families! Please watch out for the call for blood donations!

Merry Christmas 🎄 from Boc lab and Friends!

The best #postdoc and #PhD students in the world. I ❤️ doing #Science with you guys!

@krobinson204,@Boc_Lab and I have a MRC-funded PhD (see link below- deadline 10th Jan). At the Uni's of Birmingham, Oxford and @RosFrankInst, you will use advanced organoid and microscopy technologies to understand how we can target the microbiome for stomach cancer prevention.

Today, @ClaudiaZagami successfully defended her #PhD #thesis! 🎉 This marks the culmination of an incredible journey of #discovery, driven by your boundless #curiosity, #passion, and #dedication. May the force always be with you on your next adventure!

@KimberlyHartl_ @ScienceAdvances @LabSigal Well done Kimberly!

Great to be at the Oxford #Stem #Cell institute annual symposium!

Looking forward to meeting the scientific community @i3S_UPorto! Thanks, @malino81 for the invitation!

/3 But, Helicobacter pylori can weaken this defence increasing the risk of developing #stomach cancer Thanks @Ludwig_Cancer for the great support! #organoids #innateimmunity

1/2 These are natural antibiotics that we produce to turn mucus into a germ-killing weapon. We have used our #mucosoids to study this. We found #inflammation triggers cells to release germ-fighting proteins into mucus, which can fend off stomach bugs like #Helicobacter pylori.

Mucus protect us from infections, but how? Check our latest publication on Gut Microbes @tandfonline! #d1e483" target="_blank" rel="nofollow noopener">tandfonline.com/doi/full/10.10…. #Mucus in our gut isn't just a gel barrier; it fights microbes too! When our #gut gets inflamed, it makes #antimicrobial peptides. (1/1)

Hiring! We are looking for a full-time research assistant to join our team at @RosFrankInst to develop organoid systems for workflows on advance imaging. Exciting science and team! #newPI More information below👇 . opportunities.rfi.ac.uk/vacancy/resear…

Summer celebration! Congrats to Rania for her BSc and welcome to Artin and Rachel!

Interesting study showing how #hpylori mediates epithelial barrier disruption using #Mucosoids. HtrA-Dependent E-Cadherin Shedding Impairs the Epithelial Barrier Function in Primary Gastric Epithelial Cells and Gastric Organoids mdpi.com/2848196 #mdpiijms via @IJMS_MDPI

We are hiring a #postdoc to study the #biology of #epithelial barriers. Join us @Ludwig_Cancer @UniofOxford. apply here! my.corehr.com/pls/uoxrecruit…

Nice study showing how #mucosoids can help to undestand #metaplasia in the #stomach. …nslational-medicine.biomedcentral.com/articles/10.11…

Thanks #leeplacito! This is a great opportunity to continue our efforts in understanding the origin of #stomach #cancer.